Punica granatum L. peel extract protects diabetic nephropathy by activating the Nrf-2/HO-1 pathway

Betül Apaydın Yıldırım, Tuba Karaarslan, Esra Aktas Senocak, Serkan Yıldırım, Saban Kordali, Fatih Yıldırım

• WoS Q3
• Scopus Q2
• WoS 6 atıf

Osajin, sıçan sepsis modelinde 8-OHdG/Bax/Kaspaz-3 yolunun bastırılması yoluyla sepsis ile indüklenen beyin hasarı için umut verici bir adaydır

Mohammad ALHILAL, Serkan Yıldırım, Huseyin Serkan Erol, Suzan Alhilal, Metin Kiliçlioğlu, Berrah GÖZEGİR, murat koç, Mesut Bünyami Halıcı

Ratlarda ovariohisterektomiyi takiben tek başına veya okside rejenere selüloz ile birlikte rifampisin kullanılarak intraabdominal adezyonun önlenmesi

Damla Tuğçe Okur, Şifanur Aydin, Sıtkıcan Okur, Ayşe Gölgeli Bedir, Ömer Tarık Orhun, Vefa Tohumcu, Serkan Yıldırım, Yavuz Sağlam, Şaab Elban

Trigonelline alkaloid is effective in preventing doxorubicin-induced lung damage

Hamit Uslu, Gozde Atila Uslu, Betuel Cicek, İsmail Bolat, Serkan Yıldırım

• WoS Q2
• Scopus Q1
• WoS 6 atıf

In Vitro Effect of Boron Compounds in Combination with Photobiomodulation Therapy by 905 nm on the Viability of Human Gingival Fibroblasts

Ferda Turgut, Latif Emrah Yanmaz, Serkan Yıldırım, Ali Taghızadehghalehjoughı, Yesim Yenı, Sıtkıcan Okur, Omer Tarik Orhun

• WoS Q2
• Scopus Q2

Gallic acid’s protective mechanisms against acrylamide‑induced pulmonary injury: in vivo and in silico insights into the Nrf‑2/HO‑1/ NFκB pathway modulation

Merve Bolat, Samet Tekin, İsmail Bolat, Aslıhan Atasever, Burak Çınar, Yusuf Dağ, Emin Şengül, Serkan Yıldırım, Mohamad Alı Ahmad Warda, Fikret Çelebi

• WoS Q2
• Scopus Q2

Mechanistic insights into the P-coumaric acid protection against bisphenol A-induced hepatotoxicity in in vivo and in silico models

Samet Tekin, Merve Bolat, Aslıhan Atasever, İsmail BOLAT, Burak Çınar, Azızeh Shadıdızajı, Yusuf Dağ, Emin Şengül, Serkan Yıldırım, Ahmet Hacımüftüoğlu, Mohamad Alı Ahmad Warda

• WoS Q1
• Scopus Q1
• WoS 9 atıf
• PlumX

Evaluation of the effects of carbamazepine-loaded chitosan-coated PLGA-Zein nanoparticles on pilocarpine-induced seizure model in zebrafish larvae: developmental toxicity and behavioral assays

Gonca Alak, Serkan Yıldırım, Afife Büşra Uğur Kaplan, Mine Köktürk, Dilek Nazli, Berrah Gözegir, Gunes Ozhan, Meltem Çetin

• WoS Q2
• Scopus Q2
• WoS 4 atıf
• Scopus 5 atıf
• PlumX

Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats

Hong Yang, Cheng Zhang, Woonghee Kim, Mengnan Shi, Metin Kiliçlioğlu, Cemil Bayram, İsmail Bolar, Ozlem Ozdemir Tozlu, Cem Baba, Nursena Yuksel, Serkan Yıldırım, Shazia Iqbal ve 6 yazar daha

• WoS Q1
• Scopus Q1
• WoS 4 atıf
• PlumX

Boric acid impedes glioblastoma growth in a rat model: insights from multi-approach analysis

Hasan Türkez, Fatih Alper, Cemil Bayram, Cem Baba, Edanur Yıldız, Melik Saracoglu, Muhammed Küçük, Berrah Gozegir, Metin Kiliçlioğlu, Mustafa Yeşilyurt, Ozlem Ozdemir Tozlu, İsmail Bolat ve 10 yazar daha

• WoS Q2
• Scopus Q1
• WoS 2 atıf
• PlumX

Effect of low- and high-dose methotrexate on wound healing in rats

Abdullah Karasu, Yağmur Kuşçu, Caner Kayıkcı, Serkan Yıldırım, Oğuzhan Kuşcu, Metin KİLİÇLİOĞLU

• WoS Q3
• Scopus Q2
• WoS 3 atıf

Effects of Silymarin on immunohistochemical Bax and 8-Ohdg expression, biochemical markers and sperm parameters in an experimental varicocele model in rats

Saadet Belhan, Caner Kayıkcı, Ahmet Ufuk Kömüroğlü, Uğur Özdek, Serkan Yıldırım

• WoS Q4
• Scopus Q4

Cellular pathophysiology of Leptospira interrogans infection in canine testicular tissue: role of the TLR4/NF-kB/JNK pathway

İsmail BOLAT, Merve Bolat, Metin Kiliçlioğlu, Serkan Yıldırım, Yavuz Selim Sağlam, Selim ÇOMAKLI, Berrah Gözegir

• WoS Q3
• Scopus Q2
• WoS 15 atıf

Differential TLR2 and TLR4 mediated inflammatory and apoptotic responses in asymptomatic and symptomatic Leptospira interrogans infections in canine uterine tissue

İsmail Bolat, Merve Bolat, Metin Kiliçlioğlu, Serkan Yıldırım, Yavuz Selim Sağlam, Selim Çomaklı, Berrah Gözegir, Murat Özmen, Mohamad Alı Ahmad Warda

• WoS Q2
• Scopus Q1
• WoS 20 atıf

Multi-omics characterization of improved cognitive functions in Parkinson's disease patients after the combined metabolic activator treatment: a randomized, double-blinded, placebo-controlled phase II trial

Burak Yulug, Ozlem Altay, Xiangyu Li, Lütfü HANOĞLU, Seyda Cankaya, Halil A. Velioglu, Simon Lam, Hong Yang, Ebru Coskun, Ezgi Idil, Zubeyir Bayraktaroglu, Rahim Nogaylar ve 16 yazar daha

• Scopus Q1
• WoS 9 atıf
• PlumX

Pregabalin and Gabapentin's Roles in Nerve Regeneration: Multifaceted Analysis in an Experimental Model

Neslihan Kucun, İrem Ateş, Esra LALOĞLU, Sevilay Özmen, Serkan Yıldırım, Basri Pur, Berrah Gozegir, Mine Celik, Duygu Kose, BAHAR IŞIK

• WoS Q4
• Scopus Q3
• PlumX

Protective Effects of Baicalein and Bergenin Against Gentamicin-Induced Hepatic and Renal Injuries in Rats: An Immunohistochemical and Biochemical Study

Fazile Nur Ekinci Akdemir, Serkan Yıldırım, Fatih Mehmet Kandemir, Sefa Küçükler, Ersen Eraslan, Mustafa Can Güler

• WoS Q2
• Scopus Q2
• WoS 8 atıf
• PlumX

Pregabalin as a neuroprotective alternative to methylprednisolone in peripheral nerve regeneration: an experimental study

İrem Ateş, Esra Laloğlu, Neslihan Küçün, Sevilay Özmen, Serkan Yıldırım, Basri Pür, Duygu Köse, Maide Sena Civelek, Agah Kahramanlar, Bahar Işık, Ali Ahıskalıoğlu, İsmail Bolat

• WoS Q2
• Scopus Q2
• WoS 1 atıf
• PlumX

Effect of Microbial Phytase Addition at Different Ratios to Quail Rations on Performance Parameters and Some Carcass Values

Muhammet Ali Tunç, K. Onk, Serkan Yıldırım, Hayrunnisa Nadaroğlu, Mahir Murat Cengiz, Ahmet ADIGÜZEL

• WoS Q3
• Scopus Q3
• PlumX

Betanin ameliorates lipopolysaccharide-caused testis damage via multiple signal networks

Fatime Geyikoğlu, Gülşah Yıldız Deniz, Merve Arslan, Serkan Yıldırım, Neslihan Yuce, Turgay Şişman, Metin Kiliçlioğlu, İsmail Bolat, Suat Çolak, Muhammet Çelik, Huseyin Serkan Erol

• WoS Q3
• Scopus Q1
• WoS 2 atıf
• Scopus 1 atıf
• PlumX

Comparative evaluation of chitligsan nanosuspension gel and spray for enhancing full-thickness wound healing in a rat model

Taner Arslan, Sıtkıcan Okur, Esra Modoğlu, Ayşe Gölgeli Bedir, Emrah Özakar, Serkan Yıldırım, İsmail Bolat, Yasemin Akçora

• WoS Q3
• Scopus Q2
• WoS 5 atıf
• Scopus 5 atıf
• PlumX

Impact of apoptosis and oxidative stress on pancreatic beta cell pathophysiology in streptozotocin-induced Type 1 diabetes mellitus

ORHAN YAVUZ, Serkan Yıldırım, Serkan Yildirim, Saeed El-Ashram, Ebtesam Al-Olayan

• WoS Q1
• Scopus Q3
• WoS 15 atıf

Ameliorating effect of S-Allyl cysteine (Black Garlic) on 6-OHDA mediated neurotoxicity in SH-SY5Y cell line

Yesim Yeni, Betül Çiçek, Serkan Yıldırım, İsmail Bolat, Ahmet Hacımüftüoğlu

• Scopus Q1
• PlumX

Caftaric acid attenuates kidney and remote organ damage induced by renal ischemia-reperfusion injury

Fazile Nur Ekinci Akdemir, Mustafa Can Güler, Ersen Eraslan, Ayhan Tanyeli, Serkan Yıldırım

• WoS Q1
• Scopus Q1
• WoS 6 atıf
• PlumX

Mitigation of Acute Hepatotoxicity Induced by Cadmium Through Morin: Modulation of Oxidative and Pro-apoptotic Endoplasmic Reticulum Stress and Inflammatory Responses in Rats

Emin Şengül, Serkan Yıldırım, İrfan Cinar, Samet Tekin, Yusuf Dag, Merve Bolat, Melahat Gok, Mohamad Alı Ahmad Warda

• WoS Q2
• Scopus Q1
• WoS 27 atıf

Effect of boramidic acid modified carbon nanotubes on neurological, morphological and physiological responses of zebrafish (Danio rerio) embryos and larvae

Aybek Yigit, Mine Ko Kokturk, Serkan Yıldırım, Dilek Nazli, Metin Kiliçlioğlu, Ayse Sahin, Muhammed Atamanalp, Gunes Ozhan, Nurettin Menges, Gonca Alak

• WoS Q1
• Scopus Q1
• WoS 8 atıf
• PlumX

Eugenol alleviates the negative effects of experimental periodontitis and regulates adipokine hormones in rats

Sema Nur Sevinç Gül, Didem Özkal Eminoğlu, Emre Tekçe, Bülent Bayraktar, Leyla Güven, Alparslan Dilsiz, Serkan Yıldırım, Ahmet Sait

• WoS Q2
• Scopus Q1
• WoS 2 atıf
• Scopus 2 atıf
• PlumX

Elucidating the Molecular Mechanism by Which Gallic Acid Alleviates Oxidative Stress and Inflammatory Response of Acrylamide-Induced Renal Injury in a Rat Model Bir Rat Modelinde Gallik Asidin Oksidatif Stresi ve Akrilamid Kaynaklı Böbrek Hasarının İnflamatuar Yanıtını Hafiflettiği Moleküler Mekanizmanın Aydınlatılması

Samet Tekin, Serkan Yıldırım, Merve Bolat, Emin Şengül, Mohamad Alı Ahmad Warda

• Scopus Q4

Morinda citrifolia protective effects on paclitaxel-induced testis parenchyma toxicity: An experimental study

SIDIKA GENÇ, BETÜL ÇİÇEK, Yesim Yeni, MEHMET KUZUCU, Ahmet Hacımüftüoğlu, İsmail BOLAT, Serkan Yıldırım, Himasadat Zaker, Athanasios Zachariou, Nikolaos Sofikitis, Charalampos Mamoulakis, Aristidis Tsatsakis ve 1 yazar daha

• WoS Q2
• Scopus Q2
• WoS 5 atıf
• PlumX

Analyzing the impact of synthetic and natural steroids: a study of cytochrome P450 metabolism, morphological alterations through metabolomics, and histopathological Examination

Esat Mahmut Kocaman, Onur Şenol, Serkan Yıldırım, Muhammed Atamanalp, Sinan Özcan, İsmail Bolat, Arzu Uçar, Metin Kiliçlioğlu, Veysel Parlak, Mehmet Takkaç, Gonca Alak

• WoS Q3
• Scopus Q2
• WoS 5 atıf
• Scopus 5 atıf
• PlumX

Activity of zinc oxide and zinc borate nanoparticles against resistant bacteria in an experimental lung cancer model

Demet Çelebi, Özgür Çelebi, ALI TAGHIZADEHGHALEHJOUGHI, Sumeyye Baser, ELİF AYDIN, Daniela Calina, Ekaterina Charvalos, Anca Oana Docea, Aristidis Tsatsakis, Yaroslav Mezhuev, Serkan Yıldırım

• WoS Q3
• Scopus Q3
• WoS 9 atıf
• PlumX

Vitamins Can Increase Antibiotic Effects Against Multidrug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii in an In Vitro Infection Model

Özgür Çelebi, Demet Çelebi, Sümeyye Başer, AYŞEGÜL YILMAZ, Serkan Yıldırım

• Scopus Q2
• WoS 8 atıf
• PlumX

Protective Effects of Tea Leaf Extract (Camellia sinensis) Against Cypermethrin-Induced Toxicity in Gill and Liver of Rainbow Trout (Oncorhynchus mykiss)

TAYFUN KARATAŞ, Betül Apaydın Yıldırım, Serkan Yıldırım

• WoS Q4
• Scopus Q4
• WoS 1 atıf

Molecular insights into the antioxidative and anti-inflammatory effects of P-coumaric acid against bisphenol A-induced testicular injury: In vivo and in silico studies

Samet Tekin, Emin Sengul, Serkan Yıldırım, Emrah Hicazi Aksu, İsmail Bolat, Burak Çınar, Azızeh Shadıdızajı, Fikret Çelebi, Mohamad Alı Ahmad Warda

• WoS Q2
• Scopus Q2
• WoS 19 atıf

Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases

Ozlem Altay, Hong Yang, Serkan Yıldırım, Cemil Bayram, İsmail BOLAT, Sena Oner, Ozlem Ozdemir Tozlu, Mehmet Enes Arslan, Ahmet Hacımüftüoğlu, Saeed Shoaie, Cheng Zhang, Jan Borén ve 3 yazar daha

• WoS Q1
• Scopus Q1
• WoS 7 atıf
• PlumX

Investigation of the protective effect of chitosan against arsenic-induced nephrotoxicity and oxidative damage in rat kidney tissue

K. İrak, Öy. Çelik, M. Bolacalı, T. Tufan, S. Özcan, Serkan Yıldırım, İsmail Bolat

• WoS Q3
• Scopus Q3
• WoS 2 atıf

Effect of fentanyl and remifentanil on neuron damage and oxidative stress during induction neurotoxicity

Ali Taghizadehghalehjoughi, Muhammet Emin Naldan, Yeşim YENİ, Sidika Genc, Ahmet Hacımüftüoğlu, Mesut Isik, Adem Necip, İsmail BOLAT, Serkan Yıldırım, Sukru Beydemir, Mahmut Baykan

• WoS Q2
• Scopus Q1
• WoS 13 atıf
• PlumX

Effects of protocatechuic acid against cisplatin-induced neurotoxicity in rat brains: an experimental study

Handan Mert, Oezge Kerem, Leyla Mis, Serkan Yıldırım, Nihat Mert

• WoS Q4
• Scopus Q3
• WoS 17 atıf

Antidiabetic Effect of Fig Seed Oil in Rats with Diabetes Induced by Streptozotocin

Handan Mert, Nihan Mert, Salih Çibuk, Serkan Yıldırım, Nihat Mert

• Scopus Q2
• WoS 2 atıf

The Effects of Curcumin Nanoparticles on an Experimental Diabetes Model: Reproductive Hormones, Lipid Profile and Immunohistochemical and Immunofluorescence Markers Effekte von Curcumin Nanopartikeln in einem experimentellen Diabetesmodell: Fortpflanzungshormone, Lipidprofil, immunhistochemische Marker und Immunfluoreszenzmarker

Saadet Belhan, Zübeyir Huyut, Serkan Yıldırım, Sermin Algül

• WoS Q4
• Scopus Q4

Medicinal evaluation and molecular docking study of osajin as an anti-inflammatory, antioxidant, and antiapoptotic agent against sepsis-associated acute kidney injury in rats

Mohammad Alhilal, Huseyin Serkan Erol, Serkan Yıldırım, Ahmet Cakir, MURAT KOÇ, Suzan Alhilal, Esra Dereli, Omer Alkanoglu, Volkan Ay, Ismail Can, Mesut Bünyami Halıcı

• WoS Q1
• Scopus Q2
• WoS 9 atıf

Histopathologic and Immunohistochemical Approach to a Case of Invasive Cribriform Carcinoma in Mammary Tissue of Sprague Dawley Rat

Metin Kiliçlioğlu, BERRAH GÖZEGİR, İSMAİL BOLAT, Yavuz Selim Sağlam, Serkan Yıldırım

Investigation of the effects of pulmonary adenomatosis on oxidative dna damage, inflammation, apoptosis, and autophagy in lung tissues in sheep

İsmail Bolat, Serkan Yıldırım, Yavuz Selim Sağlam, Selim Çomaklı, Metin Kiliçlioğlu, Esra Dereli

• WoS Q3
• Scopus Q2
• WoS 15 atıf

Boron Compound–Based Treatments Against Multidrug-Resistant Bacterial Infections in Lung Cancer In Vitro Model

Demet Çelebi, Özgür Çelebi, ELİF AYDIN, Sümeyye Başer, Mustafa Can Güler, Serkan Yıldırım, ALI TAGHIZADEHGHALEHJOUGHI

• WoS Q2
• Scopus Q1
• WoS 7 atıf
• PlumX

Protective effects of green tea (Camellia sinensis) extract against cypermethrin-induced neurotoxicity in rainbow trout (Oncorhynchus mykiss) brain tissues

Mürteza Çakır, TAYFUN KARATAŞ, Serkan Yıldırım

• WoS Q3
• Scopus Q2
• WoS 5 atıf
• PlumX

ADAMTS-13 and HMGB1-induced oxidative stress in Taenia multiceps-infected animals

Gungor Cagdas Dincel, ORHAN YAVUZ, Serkan Yıldırım, Ebtesam M. Al-Olayan, Saeed El-Ashram

• WoS Q1
• Scopus Q1
• WoS 5 atıf

Mitigation potential of zingerone and rutin on toxicity mechanisms of nickel to zebrafish based on morphological, DNA damage and apoptosis outcome analysis

Mine Köktürk, Serkan Yıldırım, Muhammed Atamanalp, Metin Kiliçlioğlu, Arzu Uçar, Gunes Ozhan, Gonca Alak

• WoS Q2
• Scopus Q1
• WoS 6 atıf
• PlumX

Effects of Different Stress Applications on Some Reproductive Hormones, Sperm Parameters, Lipid Profile, Immunohistochemical and Immunofluorescent Markers

SAADET BELHAN, ZÜBEYİR HUYUT, Serkan Yıldırım, SERMİN ALGÜL

The role of GRP78/ATF6/IRE1 and caspase-3/Bax/Bcl2 signaling pathways in the protective effects of gallic acid against cadmium- induced liver damage in rats

VOLKAN GELEN, Emin Şengül, Serkan Yıldırım, Irfan Cinar

• WoS Q3
• Scopus Q2
• WoS 19 atıf

Flavonoid-Rich Sambucus nigra Berry Extract Enhances Nrf2/HO-1 Signaling Pathway Activation and Exerts Antiulcerative Effects In Vivo

BETÜL ÇİÇEK, Betül DANIŞMAN, Serkan Yıldırım, Neslihan YÜCE, Dragana Nikitovic, İsmail BOLAT, MEHMET KUZUCU, Ertuğrul Ceyran, Ebru Bardas, Kirill S. Golokhvast, Aristidis Tsatsakis, Ali Taghizadehghalehjoughi

• WoS Q1
• Scopus Q1
• WoS 19 atıf

İntranöral Bupivakain, Deksmedetomidin ve Lidokain Enjeksiyonlarını Takiben Gelişebilecek Periferik Sinir Hasarının Değerlendirilmesi: Deneysel Bir Modelde Çok Yönlü Analiz

Esra Laloğlu, İrem Ateş, Serkan Yıldırım, Şeyma ÇORUH, BASRİ PÜR, Sevilay Özmen, Nergis Ulaş, Metin Kiliçlioğlu, Emir Şahan

CURRENT SITUATION OF MICROPLASTIC POLLUTION IN THE BLACK SEA (TÜRKİYE) WHITING (Merlangius merlangus)

Gonca Alak, Mine Köktürk, Süleyman Özdemir, Aslı Çilingir Yeltekin, Fatma Betül Özgeriş, Serkan Yıldırım, Arzu Uçar, Veysel Parlak, Hünkar Avni Duyar, Emre Çağlak, Muhammed Atamanalp

From the Tien-Shan to Anatolia: The Role of Fermented Flavours (Yoghurt, Katık, Tarhana) on Gut Microbiota

Özlem Barış, Serkan Yıldırım

PREGABALİN SİNİR İYLEŞMESİNDE STEROİDLERE ALTERNATİF OLABİLİR Mİ? DENEYSEL BİR ÇALIŞMA

İrem Ateş, Esra Laloğlu, NESLİHAN KÜÇÜN, Sevilay Özmen, Serkan Yıldırım, BASRİ PÜR, DUYGU KÖSE, MAİDE SENA CİVELEK, AĞAH KAHRAMANLAR, BAHAR IŞIK, ALİ AHISKALIOĞLU, İsmail BOLAT

Effect of Sand-Based Chitin Derivative Chitosan on Wound Healing in Rats

Taner Arslan, İsmail Bolat, Ayşe Gölgeli Bedir, Sıtkıcan Okur, Serkan Yıldırım

Düzenli Aerobik Yüzme Egzersizi Uygulanan Ratlarda Çaşır Otu (Prangos ferulacea) Ekstresinin Antioksidan ve Histopatolojik Etkilerinin İncelenmesi

YUNUS ÖZTAŞYONAR, Yavuz Akkuş, Elif Akkuş, Serkan Yıldırım, İSMAİL CAN, Davut Budak, Mesut Bünyami Halıcı

Caftaric Acid Reduces Ischemia-Reperfusion Mediated Kidney and Lung Injury

FAZİLE NUR EKİNCİ AKDEMİR, Mustafa Can Güler, ERSEN ERASLAN, Ayhan Tanyeli, Serkan Yıldırım

Investigation of The Effects of Sinapic Acid on Ethanol-Induced Gastric Injuries

FAZİLE NUR EKİNCİ AKDEMİR, Mustafa Can Güler, ERSEN ERASLAN, Ayhan Tanyeli, Serkan Yıldırım

Efficacy of syringic acid against cadmium-induced testicular damage in rats

ESRA DERELİ, Serkan Yıldırım, Emin Şengül

Ratlarda Deneysel Olarak Oluşturulan Diyabetik Nefropatide Morin Hidratın Koruyucu ve Destekleyici Etkilerinin Araştırılması

Serkan Yıldırım, Esra Dereli, Hüseyin Eren Yıldırım, Emin Şengül, Yavuz Selim Sağlam, Merve Bolat, Metin Kılıçlıoğlu, İsmail Bolat

Klinik Olgular

Serkan Yıldırım

Veteriner Adli Tıp Açısından Ölüm Zamanının Belirlenmesi ve Önemi

Nergis Ulaş, Kerim Emre Yanar, Serkan Yıldırım