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Review 2023 · 88 citations

Pomegranate Peel Phytochemistry, Pharmacological Properties, Methods of Extraction, and Its Application: A Comprehensive Review

Singh, Jyoti, Kaur, Hamita Preet, Verma, Anjali, Chahal, Arshminder Singh, Jajoria, Kaushal, Rasane, Prasad, Kaur, Sawinder, Kaur, Jaspreet, Gunjal, Mahendra, Ercisli, Sezai, Choudhary, Ravish, Bozhuyuk, Mehmet Ramazan, Sakar, Ebru, Karatas, Neva, Durul, Melekber Sulusoglu

Abstract

Pomegranate peel, derived from the processing of Punica granatum L. (pomegranate), has traditionally been considered agricultural waste. However, recent studies have revealed its potential as a rich source of bioactive compounds with diverse pharmacological effects. Pomegranate peel is a rich reservoir of antioxidants, polyphenols, dietary fiber, and vitamins, which contribute to its remarkable bioactivity. Studies have demonstrated the anti-inflammatory, cardioprotective, wound healing, anticancer, and antimicrobial properties of pomegranate peel owing to the presence of phytochemicals, such as gallic acid, ellagic acid, and punicalagin. The extraction of bioactive compounds from pomegranate peel requires a careful selection of techniques to maximize the yield and quality. Green extraction methods, including pressurized liquid extraction (PLE), ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), and enzyme-assisted extraction (EAE), offer efficient and sustainable alternatives to traditional methods. Furthermore, pomegranate peel has been utilized in the food industry, where it can significantly enhance the nutritional value, organoleptic characteristics, and shelf life of food products. Pomegranate peel has the potential to be used to develop innovative functional foods, nutraceuticals, and other value-added products, providing new opportunities for the pharmaceutical, cosmetic, and food industries.

Keywords
ULTRASOUND-ASSISTED EXTRACTION PHENOLIC-COMPOUNDS ANTIMICROBIAL ACTIVITY BIOACTIVE COMPOUNDS SHELF-LIFE IN-VIVO OPTIMIZATION POLYPHENOLS GREEN APOPTOSIS
WoS Categories
Chemistry, Multidisciplinary
Sustainable Development Goals
Citation
Journal
ACS OMEGA
Year
2023
Volume
8
Issue
39
Pages
35452-35469
ISSN
2470-1343
DOI
10.1021/acsomega.3c02586
WoS UID
WOS:001070431800001
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