language Türkçe
Review 2025 · 38 citations

Ferulic acid: extraction, estimation, bioactivity and applications for human health and food

Kumar, Mukul, Kaushik, Deepika, Shubham, Shubham, Kumar, Ashwani, Kumar, Vishal, Oz, Emel, Brennan, Charles, Zeng, Maomao, Proestos, Charalampos, Cadirci, Kenan, Bayrak, Muharrem, Elobeid, Tahra, Karav, Sercan, Oz, Fatih

Abstract

Ferulic acid ((E)-3-(4-hydroxy-3-methoxy-phenyl) prop-2-enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of therapeutic effects, including anti-inflammatory, antimicrobial, anticancer, antidiabetic, cardiovascular and neuroprotective activities. It is absorbed more quickly by the body and stays in the bloodstream for a longer period compared with other phenolic acids. It is widely used in the food (namely whole grains, fruits, vegetables and coffee), pharmaceutical and cosmetics industries. The current review highlights ferulic acid and its pharmacological activities, reported mechanisms of action, food applications (food preservative, food additive, food processing, food supplements and in food packaging in the form of edible films) and role in human health. In the future, the demand for ferulic acid in the food and pharmaceutical industries will increase. (c) 2024 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Keywords
ferulic acid antiapoptotic antifibrosis anti-inflammatory antioxidant bioactive component MATRIX METALLOPROTEINASES OXIDATIVE STRESS INFLAMMATION ANTIOXIDANTS
WoS Categories
Agriculture, Multidisciplinary Chemistry, Applied Food Science & Technology
Sustainable Development Goals
Citation
Journal
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
Year
2025
Volume
105
Issue
8
Pages
4168-4177
ISSN
0022-5142
eISSN
1097-0010
DOI
10.1002/jsfa.13931
WoS UID
WOS:001324160200001
Open via DOI