Naked-eye fluorescent sensor for Cu(II) based on indole conjugate BODIPY dye
Özet
A novel on/off fluorescent indole/BODIPY-based Cu2+ chemosensor (3) was synthesized by Knoevenagel condensation of BODIPY derivative 1 with 2-methyl-indole-3-carbaldehyde 2. The identity of compound 3 was confirmed by H-1 NMR, C-13 NMR, FT-IR, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and single crystal X-ray diffraction techniques. Fluorescent chemosensor (3) is found to be highly selective and sensitive for detection of Cu2+ with a color change from purple to yellow. The optical sensor features for the Cu2+ complex of 3 were investigated by UV-Vis and fluorescence spectroscopy. The addition of Cu2+ caused quenching of fluorescence intensity and the detection limit was calculated to be 0.124 mu M. Also, the stoichiometry ratio of 3+Cu2+ was obtained 2:1 by Job's plot. Live cell image, flow cytometry and cytotoxic properties of compound 3 were examined. (C) 2016 Elsevier Ltd. All rights reserved.
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
Tümay, S. O., Okutan, E., Sengul, I. F., Ozcan, E., Kandemir, H., Doruk, T., Cetin, M., & Cosut, B. (2016). Naked-eye fluorescent sensor for Cu(II) based on indole conjugate BODIPY dye. POLYHEDRON, 117, 161–171. https://doi.org/10.1016/j.poly.2016.05.056
BibTeX
@article{tumay2016-80606,
author = {Tümay, Süreyya Oğuz and Okutan, Elif and Sengul, Ibrahim F. and Ozcan, Emrah and Kandemir, Hakan and Doruk, Tuğrul and Cetin, Metin and Cosut, Bunyemin},
title = {Naked-eye fluorescent sensor for Cu(II) based on indole conjugate BODIPY dye},
journal = {POLYHEDRON},
year = {2016},
volume = {117},
pages = {161--171},
issn = {0277-5387},
doi = {10.1016/j.poly.2016.05.056},
url = {https://akademik.atauni.edu.tr/yayinlar/80606-naked-eye-fluorescent-sensor-for-cuii-based-on-indole-conjugate-bodipy-dye}
}