Synthesis and antibacterial screening of novel 2-(4-(aryl) thiazol-2-yl)-3a,4,7,7a-tetrahydro-1H-,4,7-ethanoisoindole-1,3(2H)-dione derivatives

Ozbek, Oguz; Usta, Necibe Canan; Gurdere, Meliha Burcu; Aslan, Osman Nuri; Budak, Yakup; Ceylan, Mustafa

doi:10.1080/10426507.2017.1354209

Makale Tam Makale Uluslararası 2017

Synthesis and antibacterial screening of novel 2-(4-(aryl) thiazol-2-yl)-3a,4,7,7a-tetrahydro-1H-,4,7-ethanoisoindole-1,3(2H)-dione derivatives

Oguz Ozbek, Necibe Canan Usta, Meliha Burcu Gurdere, Osman Nuri Aslan, Yakup Budak, Mustafa Ceylan

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS Cilt 192 · Sayı 10 · ss. 1153–1157 · 01.01.2017

DOI ile aç

Özet

A series of novel 2-(4-(aryl) thiazol-2-yl)-3a,4,7,7a-tetrahydro-1H-4,7-ethanoisoindole-1,3(2H)-dione derivatives were synthesized and evaluated for their antimicrobial activity. The structures of the synthesized derivatives (9a-j) were confirmed by means of IR, H-1-NMR, C-13-NMR and elemental analyses. All the compounds 9a-j showed activity against all microorganisms. Compounds 9a, 9c-d, and 9j exhibit potent antibacterial activity against tested S. pyogenes. Compounds 9c showed higher activity than standards against C. perfringes. 9a-e, 9j and 9i possess good activity against A. tumefacen.

Anahtar kelimeler

DESIGN SERIES Antibacterial activity AGENTS BIOLOGICAL EVALUATION ANTIMICROBIAL ACTIVITIES ANALOGS 4 antitumor activity Thiazole 3(2H)-dione 7-ethanoisoindole-1 2-AMINOTHIAZOLE DERIVATIVES PHTHALIMIDE DERIVATIVES THIAZOLE DERIVATIVES

Atıf için künye

Ozbek, O., Usta, N. C., Gurdere, M. B., Aslan, O. N., Budak, Y., & Ceylan, M. (2017). Synthesis and antibacterial screening of novel 2-(4-(aryl) thiazol-2-yl)-3a,4,7,7a-tetrahydro-1H-,4,7-ethanoisoindole-1,3(2H)-dione derivatives. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 192(10), 1153–1157. https://doi.org/10.1080/10426507.2017.1354209

BibTeX

@article{ozbek2017-78796,
  author = {Ozbek, Oguz and Usta, Necibe Canan and Gurdere, Meliha Burcu and Aslan, Osman Nuri and Budak, Yakup and Ceylan, Mustafa},
  title = {Synthesis and antibacterial screening of novel 2-(4-(aryl) thiazol-2-yl)-3a,4,7,7a-tetrahydro-1H-,4,7-ethanoisoindole-1,3(2H)-dione derivatives},
  journal = {PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS},
  year = {2017},
  volume = {192},
  number = {10},
  pages = {1153--1157},
  issn = {1042-6507},
  doi = {10.1080/10426507.2017.1354209},
  url = {https://akademik.atauni.edu.tr/yayinlar/78796-synthesis-and-antibacterial-screening-of-novel-2-4-aryl-thiazol-2-yl-3a477a}
}