Azaindole-BODIPYs: Synthesis, fluorescent recognition of hydrogen sulfate anion and biological evaluation

Keşan, Gürkan; Topaloğlu, Burcu; Özcan, Emrah; Kazan, Hasan Hüseyin; Tanrıverdi Eçik, Esra; Şenkuytu, Elif; Sengul, Ibrahim F.; Kandemir, Hakan; Çoşut, Bünyemin

doi:10.1016/j.saa.2019.01.047

Makale Tam Makale Uluslararası 2019

Azaindole-BODIPYs: Synthesis, fluorescent recognition of hydrogen sulfate anion and biological evaluation

Gürkan Keşan, Burcu Topaloğlu, Emrah Özcan, Hasan Hüseyin Kazan, Esra Tanrıverdi Eçik, Elif Şenkuytu, Ibrahim F. Sengul, Hakan Kandemir, Bünyemin Çoşut

Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy Cilt 213 · ss. 73–82 · 15.04.2019

DOI ile aç

Özet

The synthesized and sensing capability of two novel azaindole substituted mono and distyryl BODIPY dyes against bisulfate anion were reported. Structural characterizations of the targeted compounds were conducted by using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, H-1 and C-13 NMRspectroscopies. Photophysical properties of the azaindole substituted BODIPY compounds were investigated employing absorption and fluorescence spectroscopies in acetonitrile solution. It was found that the final compounds 3 and 4 exhibited exclusively selective and sensitive turn-off sensor behavior on HSO4- anion. Additionally, the stoichiometry ratio of the targeted compounds to bisulfate anion was measured 0.5 by Job's method. Also, density function theory was performed to the optical response of the sensor for targeted compounds. Furthermore, the cytotoxicity of Azaindole-BODIPYs was examined against living human leukemia K562 cell lines. (C) 2019 Elsevier B.V. All rights reserved.

Anahtar kelimeler

Fluorescence CHEMOSENSOR DFT HYDROGEN SULFATE Borondipyrromethenes Azaindole Anionsensor K562 cell lines

Atıf için künye

Keşan, G., Topaloğlu, B., Özcan, E., Kazan, H. H., Tanrıverdi Eçik, E., Şenkuytu, E., Sengul, I. F., Kandemir, H., & Çoşut, B. (2019). Azaindole-BODIPYs: Synthesis, fluorescent recognition of hydrogen sulfate anion and biological evaluation. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 213, 73–82. https://doi.org/10.1016/j.saa.2019.01.047

BibTeX

@article{kesan2019-78434,
  author = {Keşan, Gürkan and Topaloğlu, Burcu and Özcan, Emrah and Kazan, Hasan Hüseyin and Tanrıverdi Eçik, Esra and Şenkuytu, Elif and Sengul, Ibrahim F. and Kandemir, Hakan and Çoşut, Bünyemin},
  title = {Azaindole-BODIPYs: Synthesis, fluorescent recognition of hydrogen sulfate anion and biological evaluation},
  journal = {Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy},
  year = {2019},
  volume = {213},
  pages = {73--82},
  issn = {1386-1425},
  doi = {10.1016/j.saa.2019.01.047},
  url = {https://akademik.atauni.edu.tr/yayinlar/78434-azaindole-bodipys-synthesis-fluorescent-recognition-of-hydrogen-sulfate-anion}
}