Alterations in Growth Related Genes (GH-I, IGF-I and IGF-II) Expression with Acute Copper Exposure in Rainbow Trout
Özet
In this study, the acute effects of copper (CuSO4 center dot 5H(2)O) on the expression of Growth Hormone-I (GH-I) and Insulin like Growth Factors I and II (IGF-I and IGF-II) were investigated in rainbow trout (Oncorhynchus mykiss) muscle tissue. For this purpose, rainbow trout were exposed to 100 mu g L-1 (Sublethal concentration) copper sulfate in moderately hard freshwater. After 6, 12, 24 and 48 h of treatment, expression of white muscle GH-I, IGF-I and IGF-II mRNAs were measured by means of quantitative real-time PCR. During the exposure experiments, no mortalities occurred. All mRNA levels significantly decreased after copper administration (p<0.05). The results indicate that short term copper exposure suppresses the mRNA expression levels of GH-I, IGF-I and IGF-II in rainbow trout muscles.
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
Aksakal, E., Ceyhun, S. B., BEYDEMİR, Ş., & Erdoğan, O. (2011). Alterations in Growth Related Genes (GH-I, IGF-I and IGF-II) Expression with Acute Copper Exposure in Rainbow Trout. Journal Of Animal And Veterinary Advances, 10(25), 3334–3339. https://doi.org/10.3923/javaa.2011.3334.3339
BibTeX
@article{aksakal2011-75477,
author = {Aksakal, Ercument and Ceyhun, Saltuk Buğrahan and BEYDEMİR, ŞÜKRÜ and Erdoğan, Orhan},
title = {Alterations in Growth Related Genes (GH-I, IGF-I and IGF-II) Expression with Acute Copper Exposure in Rainbow Trout},
journal = {Journal Of Animal And Veterinary Advances},
year = {2011},
volume = {10},
number = {25},
pages = {3334--3339},
issn = {1680-5593},
doi = {10.3923/javaa.2011.3334.3339},
url = {https://akademik.atauni.edu.tr/yayinlar/75477-alterations-in-growth-related-genes-gh-i-igf-i-and-igf-ii-expression-with-acute}
}