Synthesis of bis(benzoxazole) frameworks chiralized by planar chiral [2.2]Paracyclophane

Polat, Emrah; Turbedaroglu, Ozge; Çakıcı, Murat

doi:10.1016/j.tetlet.2021.152871

Makale Tam Makale Uluslararası 2021

Synthesis of bis(benzoxazole) frameworks chiralized by planar chiral [2.2]Paracyclophane

Emrah Polat, Ozge Turbedaroglu, Murat Çakıcı

Tetrahedron Letters 01.03.2021

DOI ile aç

Özet

In this study, a new class of chiral bis(benzoxazole) has been synthesized. The bis(benzoxazole) framework, which has an achiral structure was chiralized by a planar chiral [2.2]paracyclophane moiety. Both enantiomeric forms of the bis(benzoxazole) derivatives were successfully obtained in 99% ee. Even though the starting material was not completely enantiomerically pure, enantiomeric enrichment was afforded by the Horeau principle in the synthesis route. (C) 2021 Elsevier Ltd. All rights reserved.

Anahtar kelimeler

Planar chirality Bis(benzoxazole) [2.2]Paracyclophane Horeau principle

Sürdürülebilir Kalkınma Amaçları

SKA 3: Sağlıklı Bireyler

Atıf için künye

Polat, E., Turbedaroglu, O., & Çakıcı, M. (2021). Synthesis of bis(benzoxazole) frameworks chiralized by planar chiral [2.2]Paracyclophane. Tetrahedron Letters. https://doi.org/10.1016/j.tetlet.2021.152871

BibTeX

@article{polat2021-72650,
  author = {Polat, Emrah and Turbedaroglu, Ozge and Çakıcı, Murat},
  title = {Synthesis of bis(benzoxazole) frameworks chiralized by planar chiral [2.2]Paracyclophane},
  journal = {Tetrahedron Letters},
  year = {2021},
  issn = {0040-4039},
  doi = {10.1016/j.tetlet.2021.152871},
  url = {https://akademik.atauni.edu.tr/yayinlar/72650-synthesis-of-bisbenzoxazole-frameworks-chiralized-by-planar-chiral}
}