A novel approach for the synthesis of β-keto esters: One-pot reaction of carboxylic acids with chlorosulfonyl isocyanate

Atmaca, Ufuk

doi:10.24820/ark.5550190.p011.209

Makale Tam Makale Uluslararası 2020 Açık erişimli

A novel approach for the synthesis of β-keto esters: One-pot reaction of carboxylic acids with chlorosulfonyl isocyanate

Ufuk Atmaca

ARKIVOC Cilt 6 · 01.01.2020

DOI ile aç

Özet

© AUTHOR(S).β-Keto esters were synthesized by direct carboxylation of various 4- and 5-oxo-carboxylic acid derivatives in the presence of chlorosulfonyl isocyanate in excellent yield under mild conditions. Additionally, optimization conditions were examined for synthesis β-keto esters. Finally, it has been found that trifluoroacetic acid is efficient in DCM under optimized conditions. This efficient one-pot novel method is very usefull, fair price and easy to handle of β-keto esters.

Anahtar kelimeler

ONE-POT chlorosulfonyl isocyanate Acylation Carboxylic acid beta-Keto ester trifluoroacetic acid

Atıf için künye

Atmaca, U. (2020). A novel approach for the synthesis of β-keto esters: One-pot reaction of carboxylic acids with chlorosulfonyl isocyanate. ARKIVOC, 6. https://doi.org/10.24820/ark.5550190.p011.209

BibTeX

@article{atmaca2020-72499,
  author = {Atmaca, Ufuk},
  title = {A novel approach for the synthesis of β-keto esters: One-pot reaction of carboxylic acids with chlorosulfonyl isocyanate},
  journal = {ARKIVOC},
  year = {2020},
  volume = {6},
  issn = {1551-7004},
  doi = {10.24820/ark.5550190.p011.209},
  url = {https://akademik.atauni.edu.tr/yayinlar/72499-a-novel-approach-for-the-synthesis-of-v-keto-esters-one-pot-reaction-of}
}