Synthesis and asymmetric catalytic activity of (1S,1 ' S)-4,4 '-biquinazoline-based primary amines

Çakıcı, Murat; CATIR, Mustafa; Karabuga, Semistan; Ulukanli, Sabri; Kılıç, Hamdullah

doi:10.1016/j.tetasy.2011.01.009

Makale Tam Makale Uluslararası 2011

Synthesis and asymmetric catalytic activity of (1S,1 ' S)-4,4 '-biquinazoline-based primary amines

Murat Çakıcı, Mustafa CATIR, Semistan Karabuga, Sabri Ulukanli, Hamdullah Kılıç

TETRAHEDRON-ASYMMETRY Cilt 22 · Sayı 3 · ss. 300–308 · 10.02.2011

DOI ile aç

Özet

A series of (1S,1'S)-4,4'-biquinazoline-based primary amines were prepared from natural amino acids via a six-step reaction sequence of protection and condensation followed by key synthetic steps including chlorination, nickel(0)-mediated homocoupling, and deprotection. These novel amines were screened for the asymmetric ethylation of aryl aldehydes to yield alcohols with an (S)-configuration with enantiomeric excesses (ee) varying from 2% to 95%. (C) 2011 Elsevier Ltd. All rights reserved.

Atıf için künye

Çakıcı, M., CATIR, M., Karabuga, S., Ulukanli, S., & Kılıç, H. (2011). Synthesis and asymmetric catalytic activity of (1S,1 ' S)-4,4 '-biquinazoline-based primary amines. TETRAHEDRON-ASYMMETRY, 22(3), 300–308. https://doi.org/10.1016/j.tetasy.2011.01.009

BibTeX

@article{cakici2011-71182,
  author = {Çakıcı, Murat and CATIR, Mustafa and Karabuga, Semistan and Ulukanli, Sabri and Kılıç, Hamdullah},
  title = {Synthesis and asymmetric catalytic activity of (1S,1 ' S)-4,4 '-biquinazoline-based primary amines},
  journal = {TETRAHEDRON-ASYMMETRY},
  year = {2011},
  volume = {22},
  number = {3},
  pages = {300--308},
  issn = {0957-4166},
  doi = {10.1016/j.tetasy.2011.01.009},
  url = {https://akademik.atauni.edu.tr/yayinlar/71182-synthesis-and-asymmetric-catalytic-activity-of-1s1-s-44-biquinazoline-based}
}