FUMIGANT TOXICITY OF NORBORNANETETRAACETATE, CYCLOOCTANETETRAACETATE AND 7-OXANORBORNENE DERIVATIVE AGAINST THE STORED PRODUCT INSECT PEST Sitophilus granarius (L.)

The chemical compounds norbornanetetraacetate (1b) cyclooctane-1,2,5,6-tetraacetate (2b), and lactone 3 showed fumigant toxicity against adults of Sitophilus granarius (Coleoptera: Curculionidae). The P-value tests were carried out to determine the statistical significance of dose and time combinations against the insect. Norbomanetetraacetate (1b) was the most toxic of the three compounds tested in 3 mu L (1 mu L/L air) within the first 24 h after application. The same level of toxicity was obtained with cyclooctane-1.2,5,6-tetraacetate (2b) in 3 mu L at 48 h. On the other hand, lactone 3 was the most toxic of the three compounds tested in 3 mu L (1 mu L/L air) at 72 h. In 9 L (3 mu L/L air), norbornanetetraacetate (1b) was the most toxic of the three compounds tested on adult S. granarius up to 48 h. Norbornanetetraacetate (1b) was more toxic than lactone 3 and cyclooctane-1,2,5.6-tetraacetate (2b) at 6-48 h in 9 mu L (3 mu L/L air), and as toxic as lactone 3 at 72 h. In general, norbornanetetraacetate (1b) is more toxic than cyclooctane-1.2, 5,6-tetraacetate (2b) and lactone 3 at all doses and exposure times against adult S. granarius.