A Novel Method for the Synthesis of Newfangled Asymmetric Schiff Bases from -amino Acids under Ultrasonic Conditions and in Aqueous Medium
Özet
Chiral Schiff bases were obtained at high yields via a novel technique. Aryl aldehydes and chiral -amino acids were treated (1) in the presence of H3PO4 in ethanol at 80 degrees C for 24 h, and (2) in the presence of K2CO3 under ultrasonic conditions in an aqueous ethanol medium within 5 min with yields reaching up to 96%. The results showed that the presented methodology under ultrasonic conditions was effective, practical, and eco-friendly compared to that using an acidic medium. The corresponding asymmetric Schiff bases were synthesized for the first time, and were characterized by H-1 and C-13 nuclear magnetic resonance and infrared spectroscopy and high-resolution mass spectrometry.
Anahtar kelimeler
Atıf için künye
ŞENDİL, K., Tekin, T., GÖKSU, H., Oguz, M., Anıl, B., & Gültekin, M. S. (2016). A Novel Method for the Synthesis of Newfangled Asymmetric Schiff Bases from -amino Acids under Ultrasonic Conditions and in Aqueous Medium. JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 63(9), 808–817. https://doi.org/10.1002/jccs.201600094
BibTeX
@article{sendil2016-70476,
author = {ŞENDİL, Kivilcim and Tekin, Turgay and GÖKSU, Haydar and Oguz, Mehmet and Anıl, Barış and Gültekin, Mehmet Serdar},
title = {A Novel Method for the Synthesis of Newfangled Asymmetric Schiff Bases from -amino Acids under Ultrasonic Conditions and in Aqueous Medium},
journal = {JOURNAL OF THE CHINESE CHEMICAL SOCIETY},
year = {2016},
volume = {63},
number = {9},
pages = {808--817},
issn = {0009-4536},
doi = {10.1002/jccs.201600094},
url = {https://akademik.atauni.edu.tr/yayinlar/70476-a-novel-method-for-the-synthesis-of-newfangled-asymmetric-schiff-bases-from}
}