Tirşik (Arum maculatum): zehirli bitkiden doğal bir tedavi kaynağına

“It is the dose that makes the

poison” expressed Paracelsus nearly 550 years ago as all things are poisonous

at altered concentrations<w:sdt docpart="3FA47BAE3049439FA3DB8C3D0B1B83F5" sdttag="MENDELEY_CITATION_v3_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" id="-1499647701">[1], [2]</w:sdt>. The phenomenon has been admitted by

researchers since then, and today, most of the dangerous and life-threatening

diseases have been treated by the toxins of bacterial/plant sources or venoms

of insects and herptile animals. This well-accepted way of thinking still keeps

its chair in natural product research and serves humankind in many aspects<w:sdt docpart="3FA47BAE3049439FA3DB8C3D0B1B83F5" sdttag="MENDELEY_CITATION_v3_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" id="1611854179">[2]</w:sdt>.<o:p></o:p>

Cuckoo-pint

(Arum maculatum L.) has popularity all over the world with its

attribution to poisoning characterized by skin irritation, stomachache, swollen

tongue and throat, vomiting, difficulty in breathing, arrhythmia,

hallucinations, and rarely death<w:sdt docpart="3FA47BAE3049439FA3DB8C3D0B1B83F5" sdttag="MENDELEY_CITATION_v3_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" id="1285149501">[3], [4]</w:sdt>. On the other hand, the cuckoo-pint

has been accepted as a cheap and tasty food source (after a long-lasting fermentation

process to detoxify), especially in the southern region of Turkey and the Czech

Republic as it is rich in bioactive compounds, such as alkaloids, saponin,

anthocyanidins, protein, fat, carbohydrates, vitamins and minerals<w:sdt docpart="3FA47BAE3049439FA3DB8C3D0B1B83F5" sdttag="MENDELEY_CITATION_v3_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" id="-458498300">[4], [5]</w:sdt>. <o:p></o:p>

In this

study, phytochemical characterization and determination of the biological

activity of cuckoo-pint extracts were aimed. Ethanol and water-extracted parts

of the cuckoo-pint were first subjected to LC-MS/MS and flavonoid/phenol

analysis<w:sdt docpart="3FA47BAE3049439FA3DB8C3D0B1B83F5" sdttag="MENDELEY_CITATION_v3_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" id="403346862">[6]</w:sdt>. Then, enzyme inhibition studies over

human carbonic anhydrase I and II, acetylcholine esterase, butyrylcholine

esterase, α -amylase were performed, and IC50 values were determined

for each enzyme inhibition<w:sdt docpart="3FA47BAE3049439FA3DB8C3D0B1B83F5" sdttag="MENDELEY_CITATION_v3_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" id="1145474085">[6], [7]</w:sdt>. The extracts' antioxidant capacity

and reducing ability were analyzed by DPPH, ABTS radical scavenging assay, and

FRAP, CUPRAC, and Fe+3-reducing assays, respectively<w:sdt docpart="3FA47BAE3049439FA3DB8C3D0B1B83F5" sdttag="MENDELEY_CITATION_v3_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" id="1630050177">[8]</w:sdt>. Also, antimicrobial activity

against some pan-resistant strains (Klebsiella pneumeniae, Staphylococcus

aureus, Escherichia coli, Enterococcus faecalis) was investigated by

agar-disk diffusion assay. <o:p></o:p>