Screening of antiradical and antioxidant activity of monodesmosides and crude extract from Leontice smirnowii tuber

Gülçin, İlhami; Mshvildadze, V; GEPDIREMEN, A; Elias, Riad

doi:10.1016/j.phymed.2005.03.009

Makale Tam Makale Uluslararası 2006

Screening of antiradical and antioxidant activity of monodesmosides and crude extract from Leontice smirnowii tuber

İlhami Gülçin, V Mshvildadze, A GEPDIREMEN, Riad Elias

PHYTOMEDICINE Cilt 13 · Sayı 5 · ss. 343–351 · 01.05.2006

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Özet

Leontice smirnowii is a member of the Berberidaceae family. In the current study we investigated the possible antiradical and antioxidant activity of the monodesmosides (MLS) and crude extract (CELS) of Leontice smirnowii using different antioxidant tests: 1,1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging, scavenging of superoxide anion radical-generated non-enzymatic system, ferric thiocyanate (FTC) method, reducing power, hydrogen peroxide scavenging and metal chelating activities. Experiment revealed that MLS and CELS have an antioxidant effect concentration-dependently. Total antioxidant activity was performed according to FTC method. At the 30 mu g/ml concentration, the inhibition effects of MLS and CELS on peroxidation of linoleic acid emulsion were found to be 95.3% and 95.6%, respectively. On the other hand, percentage inhibition of butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), alpha-tocopherol and trolox were found to be 98.2%, 98.5%, 84.0% and 87.9% inhibition of peroxidation of linoleic acid emulsion, respectively, at the same concentration. In addition, MLS and CELS had effective DPPH radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, reducing power and metal chelating activities. Also, these various antioxidant activities were compared with BHA, BHT, a-tocopherol and trolox which were accepted as references antioxidants. (c) 2005 Elsevier GmbH. All rights reserved.

Anahtar kelimeler

Free radicals ANTIOXIDANT ACTIVITY Radical scavenging Flavonoids OXYGEN Metal chelating monodesmosides Leontice smirnowii

Atıf için künye

Gülçin, İ., Mshvildadze, V., GEPDIREMEN, A., & Elias, R. (2006). Screening of antiradical and antioxidant activity of monodesmosides and crude extract from Leontice smirnowii tuber. PHYTOMEDICINE, 13(5), 343–351. https://doi.org/10.1016/j.phymed.2005.03.009

BibTeX

@article{gulcin2006-68069,
  author = {Gülçin, İlhami and Mshvildadze, V and GEPDIREMEN, A and Elias, Riad},
  title = {Screening of antiradical and antioxidant activity of monodesmosides and crude extract from Leontice smirnowii tuber},
  journal = {PHYTOMEDICINE},
  year = {2006},
  volume = {13},
  number = {5},
  pages = {343--351},
  issn = {0944-7113},
  doi = {10.1016/j.phymed.2005.03.009},
  url = {https://akademik.atauni.edu.tr/yayinlar/68069-screening-of-antiradical-and-antioxidant-activity-of-monodesmosides-and-crude}
}