Synthesis of dimeric phenol derivatives and determination of in vitro antioxidant and radical scavenging activities
Özet
In this study, di(2,6-dimethylphenol) (Di-DMP), di(2,6-diisopropylphenol) (Di-DIP, dipropofol) and di( 2,6-di-t-butylphenol) (Di-DTP) were synthesized by the reaction of monomeric phenol derivatives with catalytic CuCl( OH). TMEDA and Na2S2O4. Their antioxidant capacity and radical scavenging activity were examined using different in vitro methodologies such as 1,1-diphenyl- 2-picryl-hydrazyl (DPPH center dot) free radical scavenging, 2,2'-azino-bis(3-ethylbenzthiazoline6- sulfonic acid) (ABTS) radical scavenging activity, total antioxidant activity by ferric thiocyanate, total reducing power by potassium ferricyanide reduction method, superoxide anion radical scavenging, hydrogen peroxide scavenging and ferrous ions chelating activities.
Anahtar kelimeler
Atıf için künye
Gülçin, İ., & Daştan, A. (2007). Synthesis of dimeric phenol derivatives and determination of in vitro antioxidant and radical scavenging activities. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 22(6), 685–695. https://doi.org/10.1080/14756360601164903
BibTeX
@article{gulcin2007-67928,
author = {Gülçin, İlhami and Daştan, Arif},
title = {Synthesis of dimeric phenol derivatives and determination of in vitro antioxidant and radical scavenging activities},
journal = {JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY},
year = {2007},
volume = {22},
number = {6},
pages = {685--695},
issn = {1475-6366},
doi = {10.1080/14756360601164903},
url = {https://akademik.atauni.edu.tr/yayinlar/67928-synthesis-of-dimeric-phenol-derivatives-and-determination-of-in-vitro}
}