In vitro effects of some drugs on human red blood cell glucose-6-phosphate dehydrogenase enzyme activity
Özet
In vitro effects of omeprazole, morphine sulphate, remifentanyl, ketamine and vankomycin were investigated on human red blood cell glucose-6 phosphate dehydrogenase (G-6PD) (E.C. 1.1.1.49) enzyme activity purified from human red blood cell by 2', 5'ADP-Sepharose 4B affinity gel. The obtained 150 values of omeprazole, morphine, remifentanil, ketamine and vankomycin were 3.24, 43.58, 97.6, 64.16 and 0.903 mM, respectively and the K-i constants for omeprazole, morphine and vankomycin were 8.22 +/- 2.055, 25.93 +/- 6.482, and 2.71 +/- 0.677 mM, respectively and they were non competitive inhibitors.
Atıf için künye
Özdemir, H., & CIFTCI, M. (2006). In vitro effects of some drugs on human red blood cell glucose-6-phosphate dehydrogenase enzyme activity. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 21(1), 75–80. https://doi.org/10.1080/14756360500356790
BibTeX
@article{ozdemir2006-67316,
author = {Özdemir, Hasan and CIFTCI, M},
title = {In vitro effects of some drugs on human red blood cell glucose-6-phosphate dehydrogenase enzyme activity},
journal = {JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY},
year = {2006},
volume = {21},
number = {1},
pages = {75--80},
issn = {1475-6366},
doi = {10.1080/14756360500356790},
url = {https://akademik.atauni.edu.tr/yayinlar/67316-in-vitro-effects-of-some-drugs-on-human-red-blood-cell-glucose-6-phosphate}
}