Synthesis and spectral investigation of some methyl-substituted 3-(2-pyridyl)-2-(2-thienyl)thiazolidin-4-one derivatives
Özet
Some heteroaryl-substituted thiazolidin-4-one derivatives have been synthesised starting from thiophenecarbox-aldehydes, 2-amino-6-methylpyridine and 2-mercaptoacetic acid. However, the use of 2-mercaptopropanoic acid gave the thiazolidinone derivatives as a mixture of cis-and trans-isomers. The configuration of both the cis-and trans-isomers has been established by NOE-difference experiments. Furthermore, the stereochemistry of one of the trans isomers was established by X-ray crystallography.
Atıf için künye
Fidan, I., Kazaz, C., Şahin, E., & KABAN, Ş. (2010). Synthesis and spectral investigation of some methyl-substituted 3-(2-pyridyl)-2-(2-thienyl)thiazolidin-4-one derivatives. JOURNAL OF CHEMICAL RESEARCH(5), 296–300. https://doi.org/10.3184/030823410x12746350585058
BibTeX
@article{fidan2010-66822,
author = {Fidan, Ismail and Kazaz, Cavit and Şahin, Ertan and KABAN, Şeniz},
title = {Synthesis and spectral investigation of some methyl-substituted 3-(2-pyridyl)-2-(2-thienyl)thiazolidin-4-one derivatives},
journal = {JOURNAL OF CHEMICAL RESEARCH},
year = {2010},
number = {5},
pages = {296--300},
issn = {1747-5198},
doi = {10.3184/030823410x12746350585058},
url = {https://akademik.atauni.edu.tr/yayinlar/66822-synthesis-and-spectral-investigation-of-some-methyl-substituted-3-2-pyridyl-2-2}
}