An anomalous addition of chlorosulfonyl isocyanate to a carbonyl group: the synthesis of ((3aS, 7aR, E)-2-ethyl-3-oxo-2,3,3a, 4,7,7a-hexahydro-1H-isoindol-1-ylidene)sulfamoyl chloride
Özet
In this study, we developed a new addition reaction of chlorosulfonyl isocyanate (CSI), starting from 2-ethyl-3a, 4,7,7a-tetrahydro-1H- isoindole-1,3(2H)-dione. The addition reaction of CSI with 2-ethyl-3a, 4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione resulted in the formation of ylidenesulfamoyl chloride, whose exact configuration was determined by X-ray crystal analysis. We explain the mechanism of product formation supported by theoretical calculations.
Anahtar kelimeler
Atıf için künye
KÖSE, A., Unal, A., Şahin, E., BOZKAYA, U., & Kara, Y. (2019). An anomalous addition of chlorosulfonyl isocyanate to a carbonyl group: the synthesis of ((3aS, 7aR, E)-2-ethyl-3-oxo-2,3,3a, 4,7,7a-hexahydro-1H-isoindol-1-ylidene)sulfamoyl chloride. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 15, 931–936. https://doi.org/10.3762/bjoc.15.89
BibTeX
@article{kose2019-66782,
author = {KÖSE, AYTEKİN and Unal, Ash and Şahin, Ertan and BOZKAYA, UĞUR and Kara, Yunus},
title = {An anomalous addition of chlorosulfonyl isocyanate to a carbonyl group: the synthesis of ((3aS, 7aR, E)-2-ethyl-3-oxo-2,3,3a, 4,7,7a-hexahydro-1H-isoindol-1-ylidene)sulfamoyl chloride},
journal = {BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY},
year = {2019},
volume = {15},
pages = {931--936},
issn = {1860-5397},
doi = {10.3762/bjoc.15.89},
url = {https://akademik.atauni.edu.tr/yayinlar/66782-an-anomalous-addition-of-chlorosulfonyl-isocyanate-to-a-carbonyl-group-the}
}