Synthesis, characterization and antibacterial activity of new sulfonamide derivatives and their nickel(II), cobalt(II) complexes

Ozdemir, Ummuhan O.; Guvenc, Pinar; Şahin, Ertan; Hamurcu, Fatma

doi:10.1016/j.ica.2008.11.029

Makale Tam Makale Uluslararası 2009

Synthesis, characterization and antibacterial activity of new sulfonamide derivatives and their nickel(II), cobalt(II) complexes

Ummuhan O. Ozdemir, Pinar Guvenc, Ertan Şahin, Fatma Hamurcu

Inorganica Chimica Acta Cilt 362 · Sayı 8 · ss. 2613–2618 · 01.06.2009

DOI ile aç

Özet

Methanesulfonicacid hydrazide (a sulfonamide compound, msh: CH(3)SO(2)NHNH(2)) derivatives: methylsalicylaldehydemethanesulfonylhydrazone (5msalmsh), 5-methyl-2-hydroxyaceto-phenonemethane-sulfonylhydrazone (5mafmsh) and their Ni(II), Co(II) complexes have been synthesized for the first time. The structure of these sulfonamide compounds has been investigated by using elemental analyses; FT-IR, (1)H NMR, (13)C NMR, LC-MS, and UV-Vis spectrometric methods; magnetic susceptibility; conductivity measurements; thermal studies. The crystal structure of 5msalmsh has been investigated by X-ray analysis. The antibacterial activities of synthesized compounds were studied against gram positive bacteria: Staphylococcus aureus, Bacillus subtilis, and Bacillus magaterium; and gram negative bacteria: Salmonella enteritidis, and Escherichia coli by using the microdilution broth method. The biological activity screening showed that ligands have more activity than complexes against the tested bacteria. (C) 2008 Elsevier B.V. All rights reserved.

Anahtar kelimeler

ANTIMICROBIAL ACTIVITY Antibacterial activity BIOLOGICAL-ACTIVITY SULFONAMIDE DERIVATIVES SCHIFF-BASES MO CR LIGANDS Ni(II) and Co(II) complexes X-ray method MICs METAL-CARBONYLS METHANESULFONYLHYDRAZONE RE(CO)(5)BR MN(CO)(3)CP

Atıf için künye

Ozdemir, U. O., Guvenc, P., Şahin, E., & Hamurcu, F. (2009). Synthesis, characterization and antibacterial activity of new sulfonamide derivatives and their nickel(II), cobalt(II) complexes. Inorganica Chimica Acta, 362(8), 2613–2618. https://doi.org/10.1016/j.ica.2008.11.029

BibTeX

@article{ozdemir2009-66677,
  author = {Ozdemir, Ummuhan O. and Guvenc, Pinar and Şahin, Ertan and Hamurcu, Fatma},
  title = {Synthesis, characterization and antibacterial activity of new sulfonamide derivatives and their nickel(II), cobalt(II) complexes},
  journal = {Inorganica Chimica Acta},
  year = {2009},
  volume = {362},
  number = {8},
  pages = {2613--2618},
  issn = {0020-1693},
  doi = {10.1016/j.ica.2008.11.029},
  url = {https://akademik.atauni.edu.tr/yayinlar/66677-synthesis-characterization-and-antibacterial-activity-of-new-sulfonamide}
}