Atatürk Üniversitesi Atatürk Üniversitesi
Ara
Yayınlara dön
Makale Tam Makale Uluslararası 2015

The syntheses, crystal structure, thermal analysis, and anticancer activities of novel dipicolinate complexes

Nazli Uzun, Alper Tolga Colak, Fatih Mehmet Emen, Gorkem Kismali, Ogunc Meral, Merve Alpay, Gulbanu Koyundereli Cilgi, Ertan Şahin

JOURNAL OF COORDINATION CHEMISTRY Cilt 68 · Sayı 6 · ss. 949–967 · 01.01.2015
DOI ile aç

Özet

[Cu(pydc)(eim)(3)].H2O (1), [Cu(pydc)(4hp)(H2O)] (2), and [Ni(pydc)(3hp)(H2O)(2)][Cu(pydc)(3hp)(H2O)(2)].3H(2)O (3) (H(2)pydc=2,6-pyridinedicarboxylic acid or dipicolinic acid, eim=2-ethylimidazole, 4hp=4-hydroxypyridine, 3hp=3-hydroxypyridine) were synthesized and characterized by elemental analysis, spectroscopic measurements (UV-vis and IR spectra), and single-crystal X-ray diffraction. Crystal analysis revealed that the complexes extended to 3-D supramolecular networks through intermolecular H-bonding and molecular interactions between the ligand moieties and water molecules. The thermal stabilities of complexes are investigated by thermogravimetry, differential thermogravimetry, and differential thermal analysis techniques. The effects of complexes on the proliferation of HT-1080 fibrosarcoma cells were investigated using the quick cell proliferation assay. The cell viability changes were found to depend on the concentrations and type of complex.

Anahtar kelimeler

CRYSTAL-STRUCTURE ANTICONVULSANT ACTIVITIES 2 METAL-COMPLEXES LIGANDS Pyridine-2 Thermal analysis COORDINATION POLYMERS COPPER(II) COMPLEXES 6-Pyridinedicarboxylate Anticancer activities ONE-DIMENSIONAL CHANNELS 6-DICARBOXYLIC ACID ZINC(II) COMPLEXES CARCINOMA-CELLS HYDROGEN-BONDS

Atıf için künye

Uzun, N., Colak, A. T., Emen, F. M., Kismali, G., Meral, O., Alpay, M., Cilgi, G. K., & Şahin, E. (2015). The syntheses, crystal structure, thermal analysis, and anticancer activities of novel dipicolinate complexes. JOURNAL OF COORDINATION CHEMISTRY, 68(6), 949–967. https://doi.org/10.1080/00958972.2014.1003371

BibTeX 
@article{uzun2015-66646,
  author = {Uzun, Nazli and Colak, Alper Tolga and Emen, Fatih Mehmet and Kismali, Gorkem and Meral, Ogunc and Alpay, Merve and Cilgi, Gulbanu Koyundereli and Şahin, Ertan},
  title = {The syntheses, crystal structure, thermal analysis, and anticancer activities of novel dipicolinate complexes},
  journal = {JOURNAL OF COORDINATION CHEMISTRY},
  year = {2015},
  volume = {68},
  number = {6},
  pages = {949--967},
  issn = {0095-8972},
  doi = {10.1080/00958972.2014.1003371},
  url = {https://akademik.atauni.edu.tr/yayinlar/66646-the-syntheses-crystal-structure-thermal-analysis-and-anticancer-activities-of}
}