New one-pot synthesis of spiro[furo[2,3-d]pyrimidine-6,5 '-pyrimidine]pentaones and their sulfur analogues
Özet
Reaction of barbituric acid (BA), 1,3-dimethyl barbituric acid (DMBA) and 2-thiobarbituric acid (TBA) with cyanogen bromide and various aldehydes in presence of triethylamine afforded a new class of heterocyclic stable 5-alkyl and/or 5-aryl-1H, 1'H-spiro[furo[2,3-d]pyrimidine-6,5'-pyrimidine]2,2',4,4',6'(3H,3'H,5H)-pentaones which are dimeric forms of barbiturate (uracil and thiouracil derivatives) at 0 A degrees C to ambient temperatures. Structure elucidation is proved by X-ray crystallography, H-1 NMR, C-13 NMR, FT-IR, CHN and mass analyses techniques. Mechanisms of the formations are discussed.
Atıf için künye
Jalilzadeh, M., Pesyan, N. N., Rezaee, F., Rastgar, S., Hosseini, Y., & Şahin, E. (2011). New one-pot synthesis of spiro[furo[2,3-d]pyrimidine-6,5 '-pyrimidine]pentaones and their sulfur analogues. MOLECULAR DIVERSITY, 15(3), 721–731. https://doi.org/10.1007/s11030-011-9302-9
BibTeX
@article{jalilzadeh2011-66631,
author = {Jalilzadeh, Mohammad and Pesyan, Nader Noroozi and Rezaee, Fereshteh and Rastgar, Saeed and Hosseini, Yaser and Şahin, Ertan},
title = {New one-pot synthesis of spiro[furo[2,3-d]pyrimidine-6,5 '-pyrimidine]pentaones and their sulfur analogues},
journal = {MOLECULAR DIVERSITY},
year = {2011},
volume = {15},
number = {3},
pages = {721--731},
issn = {1381-1991},
doi = {10.1007/s11030-011-9302-9},
url = {https://akademik.atauni.edu.tr/yayinlar/66631-new-one-pot-synthesis-of-spirofuro23-dpyrimidine-65-pyrimidinepentaones-and}
}