Synthesis of the 3,5-diphenyl-1H-pyrazole and cytogenetic and oxidative alterations after exposure of cultured human whole blood cells
Özet
The 3,5-diphenyl-1H-pyrazole was obtained by condensation reaction of dibenzoylmethane and thiosemicarbazide in acetic acid under conventional heating and microwave irradiation method. The structure of the 3,5-diphenyl-1H-pyrazole confirmed by IR, H-1, and C-13 NMR and X-ray diffraction and the geometry optimization was carried out using density functional theory (DFT) methods at B3LYP/6-31G, 6-31G(d), 6-31G(d, p), 6-311G(d, p), 6-311G(2d, 2p), 6-31+G(d, p), 6-311++G(d, p) levels. In addition, cytotoxic and oxidative effects were investigated in cultured human peripheral blood cells.
Atıf için künye
Akbaş, E., Celikezen, F. C., Türkez, H., Ozdemir, O., Rüzgar, A., Ergan, E., & Şahin, E. (2017). Synthesis of the 3,5-diphenyl-1H-pyrazole and cytogenetic and oxidative alterations after exposure of cultured human whole blood cells. COGENT CHEMISTRY, 3(1). https://doi.org/10.1080/23312009.2017.1344115
BibTeX
@article{akbas2017-66611,
author = {Akbaş, Esvet and Celikezen, Fatih Caglar and Türkez, Hasan and Ozdemir, Ozlem and Rüzgar, Adem and Ergan, Erdem and Şahin, Ertan},
title = {Synthesis of the 3,5-diphenyl-1H-pyrazole and cytogenetic and oxidative alterations after exposure of cultured human whole blood cells},
journal = {COGENT CHEMISTRY},
year = {2017},
volume = {3},
number = {1},
issn = {2331-2009},
doi = {10.1080/23312009.2017.1344115},
url = {https://akademik.atauni.edu.tr/yayinlar/66611-synthesis-of-the-35-diphenyl-1h-pyrazole-and-cytogenetic-and-oxidative}
}