Synthesis of Pyrrole-Fused C,N-Cyclic Azomethine Imines and Pyrazolopyrrolopyrazines: Analysis of Their Aromaticity Using Nucleus-Independent Chemical Shifts Values
Özet
The AgOTf-catalyzed reaction of C-2 substituted pyrrole hydrazones having an N-propargyl group was studied. The selective 6-endo-dig mode of cyclization was observed, giving rise to the formation of pyrrole-fused C,N-cyclic azomethine imine derivatives. The reaction of one azomethine imine derivative with various dipolarophiles resulted in the formation of cycloadducts having a pyrazolopyrrolopyrazine skeleton. The aromaticity of C,N-cyclic azomethine imines as well as that of pyrazolopyrrolopyrazines was determined by calculating of nucleus-independent chemical shifts values.
Atıf için künye
Ozer, M. S., Menges, N., Keskin, S., Şahin, E., & Balci, M. (2016). Synthesis of Pyrrole-Fused C,N-Cyclic Azomethine Imines and Pyrazolopyrrolopyrazines: Analysis of Their Aromaticity Using Nucleus-Independent Chemical Shifts Values. ORGANIC LETTERS, 18(3), 408–411. https://doi.org/10.1021/acs.orglett.5b03434
BibTeX
@article{ozer2016-66531,
author = {Ozer, Merve Sinem and Menges, Nurettin and Keskin, Selbi and Şahin, Ertan and Balci, Metin},
title = {Synthesis of Pyrrole-Fused C,N-Cyclic Azomethine Imines and Pyrazolopyrrolopyrazines: Analysis of Their Aromaticity Using Nucleus-Independent Chemical Shifts Values},
journal = {ORGANIC LETTERS},
year = {2016},
volume = {18},
number = {3},
pages = {408--411},
issn = {1523-7060},
doi = {10.1021/acs.orglett.5b03434},
url = {https://akademik.atauni.edu.tr/yayinlar/66531-synthesis-of-pyrrole-fused-cn-cyclic-azomethine-imines-and}
}