Regioselective synthesis of the 3,4-dihydrofuro[3,2-d]pyrimidin-2(1H)-one skeleton: a new class of compound

Koza, Gani; Ozcan, Sevil; Şahin, Ertan; Balci, Metin

doi:10.1016/j.tet.2009.05.090

Makale Tam Makale Uluslararası 2009

Regioselective synthesis of the 3,4-dihydrofuro[3,2-d]pyrimidin-2(1H)-one skeleton: a new class of compound

Gani Koza, Sevil Ozcan, Ertan Şahin, Metin Balci

TETRAHEDRON Cilt 65 · Sayı 31 · ss. 5973–5976 · 01.08.2009

DOI ile aç

Özet

We hereby report the first preparation of the 3,4-dihydrofuro[3,2-d]pyrimidin-2(1H)-one skeleton formed by two controlled Curtius rearrangements of the corresponding acyl azides, prepared from 2-(2-methoxy-2-oxoethyl)furan-3-carboxylate via the hydrazide. Rearrangement of the acyl azides followed by trapping by nucleophiles and intramolecular trapping provided the target compounds. (C) 2009 Elsevier Ltd. All rights reserved.

Atıf için künye

Koza, G., Ozcan, S., Şahin, E., & Balci, M. (2009). Regioselective synthesis of the 3,4-dihydrofuro[3,2-d]pyrimidin-2(1H)-one skeleton: a new class of compound. TETRAHEDRON, 65(31), 5973–5976. https://doi.org/10.1016/j.tet.2009.05.090

BibTeX

@article{koza2009-66529,
  author = {Koza, Gani and Ozcan, Sevil and Şahin, Ertan and Balci, Metin},
  title = {Regioselective synthesis of the 3,4-dihydrofuro[3,2-d]pyrimidin-2(1H)-one skeleton: a new class of compound},
  journal = {TETRAHEDRON},
  year = {2009},
  volume = {65},
  number = {31},
  pages = {5973--5976},
  issn = {0040-4020},
  doi = {10.1016/j.tet.2009.05.090},
  url = {https://akademik.atauni.edu.tr/yayinlar/66529-regioselective-synthesis-of-the-34-dihydrofuro32-dpyrimidin-21h-one-skeleton-a}
}