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Makale Tam Makale Uluslararası 2005

The protective role of selenium against the genotoxicity induced by aflatoxin B-1 in root cells of crop plants

Güleray Ağar, L ALPSOY, N YILDIRIM

FRESENIUS ENVIRONMENTAL BULLETIN Cilt 14 · Sayı 10 · ss. 849–853 · 01.01.2005

Özet

The protective role of selenium against the genotoxicity induced by aflatoxin B-1 (AFB(1)) was studied in root cells of crop plants. Experimental evidences showed that chromosomal aberrations can be induced by all treated AFB(1) doses (0.1, 0.2 and 0.4 ppm). On the other hand, the frequencies of chromosomal aberration can be effectively decreased by treatment with sodium selenite (Na2SeO3, 0.08, 8 and 800 ppm) together with AFB(1). These results suggest that selenium could effectively inhibit AFB(1) induced chromosomal aberration which may be partially responsible for its mutagenic effect. Besides, the protective role of selenium against aflatoxin B, induced chromosomal aberrations is correlated with its concentrations.

Anahtar kelimeler

SELENIUM DAMAGE GENOTOXICITY rats CALCIUM liver VITAMIN-E Aflatoxin B-1 chromosome aberrations COVALENT BINDING DIETARY SELENIUM Zea mays VICIA-FABA ADDUCT FORMATION METABOLITE

Atıf için künye

Ağar, G., ALPSOY, L., & YILDIRIM, N. (2005). The protective role of selenium against the genotoxicity induced by aflatoxin B-1 in root cells of crop plants. FRESENIUS ENVIRONMENTAL BULLETIN, 14(10), 849–853.

BibTeX 
@article{agar2005-61077,
  author = {Ağar, Güleray and ALPSOY, L and YILDIRIM, N},
  title = {The protective role of selenium against the genotoxicity induced by aflatoxin B-1 in root cells of crop plants},
  journal = {FRESENIUS ENVIRONMENTAL BULLETIN},
  year = {2005},
  volume = {14},
  number = {10},
  pages = {849--853},
  issn = {1018-4619},
  url = {https://akademik.atauni.edu.tr/yayinlar/61077-the-protective-role-of-selenium-against-the-genotoxicity-induced-by-aflatoxin-b}
}