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Makale Tam Makale Uluslararası 2015

DETERMINATION OF ANTIGENOTOXIC EFFECTS OF FOUR LICHEN SPECIES BY USING HUMAN LYMPHOCYTES

Mustafa Anar, Ali Aslan, Selcuk Ceker, Hamit Emre KIZIL, Lokman Alpsoy, Güleray Ağar

FRESENIUS ENVIRONMENTAL BULLETIN Cilt 24 · Sayı 12 · ss. 4251–4256 · 01.01.2015

Özet

In this study, the geno-toxic and antigeno-toxic properties of the total extracts of four lichen species were investigated by using human lymphocytes. We obtained total extracts from R. farinacea, X parietina, U articulata and U. filipendula lichen species. The results of our studies showed that 5 mu M concentrations of AFB(1) changed the frequencies of micronucleus (MN) and malondialdehyde (MDA) levels, as well as superoxide dismutase (SOD), glutathione (GSH) and glutathione peroxidase (GPx) activities. When 5, 10 and 20 mu g/ml concentrations of total extract were added to AFB(1), the frequencies of MN and MDA levels were decreased, and SOD, GSH and GPx levels were increased. Consequently, our findings show that four lichen total extracts have strong antigenotoxic properties against aflatoxin B-1.

Anahtar kelimeler

DAMAGE antioxidant TISSUES Glutathione EXTRACTS Cytotoxic activity Indomethacin Usnea longissima Ramalina farinacea (L.) Ach. Xanthoria parietina (L.) Th. Fr. Usnea articulata Usnea filipendula AFB(1) antimutagenic antigenotoxic AFLATOXINS AFRICA

Atıf için künye

Anar, M., Aslan, A., Ceker, S., KIZIL, H. E., Alpsoy, L., & Ağar, G. (2015). DETERMINATION OF ANTIGENOTOXIC EFFECTS OF FOUR LICHEN SPECIES BY USING HUMAN LYMPHOCYTES. FRESENIUS ENVIRONMENTAL BULLETIN, 24(12), 4251–4256.

BibTeX 
@article{anar2015-61023,
  author = {Anar, Mustafa and Aslan, Ali and Ceker, Selcuk and KIZIL, Hamit Emre and Alpsoy, Lokman and Ağar, Güleray},
  title = {DETERMINATION OF ANTIGENOTOXIC EFFECTS OF FOUR LICHEN SPECIES BY USING HUMAN LYMPHOCYTES},
  journal = {FRESENIUS ENVIRONMENTAL BULLETIN},
  year = {2015},
  volume = {24},
  number = {12},
  pages = {4251--4256},
  issn = {1018-4619},
  url = {https://akademik.atauni.edu.tr/yayinlar/61023-determination-of-antigenotoxic-effects-of-four-lichen-species-by-using-human}
}