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Makale Tam Makale Uluslararası 2015

Genotoxic, antigenotoxic and antioxidant properties of methanol extracts obtained from Peltigera horizontalis and Peltigera praetextata

Gökçe Karadayı, Derya YANMIS, Lokman Alpsoy, Medine GÜLLÜCE, Güleray Ağar, Ali Aslan

TOXICOLOGY AND INDUSTRIAL HEALTH Cilt 31 · Sayı 7 · ss. 602–613 · 01.01.2015
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Özet

Now-a-days, there is a big need to reduce genotoxic effects of mutagenic and carcinogenic agents in environment, which are increased by the technological development. Lichens produce a wide variety of unique metabolites due to being in various extreme areas and being symbiotic organisms of fungi and algae. Therefore, this study was planned to search new sources having antimutagenic activity by researching two different lichen species and to determine whether their usage is safe. With this respect, the mutagenic and antimutagenic properties of methanol extracts of the lichens were determined by the bacterial reverse mutation and sister chromatid exchange assays. Furthermore, the malondialdehyde level, superoxide dismutase, glutathione and glutathione peroxidase activities against aflatoxin BI were determined for understanding the ways in which the lichens showed their genotoxic properties.

Anahtar kelimeler

oxidative stress ANTIOXIDANT ENZYMES EASTERN ANATOLIA REGION ESCHERICHIA-COLI Saccharomyces cerevisiae SODIUM-AZIDE antigenotoxicity ANTIMUTAGENIC ACTIVITIES ACTIVE OXYGEN SCE) Peltigera sp. bacterial reverse mutation assay LICHEN SECONDARY METABOLITES OXIDIZED GLUTATHIONE MUTAGENIC-ACTIVITY

Sürdürülebilir Kalkınma Amaçları

  • SKA 17: Amaçlar için Ortaklıklar

Atıf için künye

Karadayı, G., YANMIS, D., Alpsoy, L., GÜLLÜCE, M., Ağar, G., & Aslan, A. (2015). Genotoxic, antigenotoxic and antioxidant properties of methanol extracts obtained from Peltigera horizontalis and Peltigera praetextata. TOXICOLOGY AND INDUSTRIAL HEALTH, 31(7), 602–613. https://doi.org/10.1177/0748233713480207

BibTeX 
@article{karadayi2015-60990,
  author = {Karadayı, Gökçe and YANMIS, Derya and Alpsoy, Lokman and GÜLLÜCE, Medine and Ağar, Güleray and Aslan, Ali},
  title = {Genotoxic, antigenotoxic and antioxidant properties of methanol extracts obtained from Peltigera horizontalis and Peltigera praetextata},
  journal = {TOXICOLOGY AND INDUSTRIAL HEALTH},
  year = {2015},
  volume = {31},
  number = {7},
  pages = {602--613},
  issn = {0748-2337},
  doi = {10.1177/0748233713480207},
  url = {https://akademik.atauni.edu.tr/yayinlar/60990-genotoxic-antigenotoxic-and-antioxidant-properties-of-methanol-extracts-obtained}
}