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Makale Tam Makale Uluslararası 2015

Ultrasonic synthesis, characterization of -aminoketones by bismuth(III) triflate and determination of antigenotoxic properties

S. Arda Ozturkcan, Kadir TURHAN, Zühal TURGUT, Mehmet Karadayı, Medine GÜLLÜCE

TOXICOLOGY AND INDUSTRIAL HEALTH Cilt 31 · Sayı 10 · ss. 911–919 · 01.10.2015
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Özet

Direct-type catalytic Mannich reaction for the synthesis of -aminoketones from cyclohexanone, substituted aromatic amines and aromatic or hetero-aromatic aldehydes has been applied in water with bismuth triflate under ultrasound. Good yields of the expected -aminoketones were obtained from available substrates, at room temperature in 1-2 hours. This study was designed to evaluate the mutagenic and antimutagenic potential of synthesized -aminoketones compounds using Ames/Salmonella and Escherichia coli WP2 bacterial reverse mutation assay systems.

Anahtar kelimeler

EASTERN ANATOLIA REGION REVERSE MUTATION ASSAY MUTAGENICITY ASSAY AQUEOUS-MEDIA beta-aminoketones direct-type Mannich reaction ultrasonic synthesis bismuth(III) triflate antigenotoxic properties MANNICH-TYPE REACTION NITRO-N-NITROSOGUANIDINE ANTIMUTAGENIC ACTIVITIES SOLVENT-FREE 3-COMPONENT

Atıf için künye

Ozturkcan, S. A., TURHAN, K., TURGUT, Z., Karadayı, M., & GÜLLÜCE, M. (2015). Ultrasonic synthesis, characterization of -aminoketones by bismuth(III) triflate and determination of antigenotoxic properties. TOXICOLOGY AND INDUSTRIAL HEALTH, 31(10), 911–919. https://doi.org/10.1177/0748233713484649

BibTeX 
@article{ozturkcan2015-55959,
  author = {Ozturkcan, S. Arda and TURHAN, Kadir and TURGUT, Zühal and Karadayı, Mehmet and GÜLLÜCE, Medine},
  title = {Ultrasonic synthesis, characterization of -aminoketones by bismuth(III) triflate and determination of antigenotoxic properties},
  journal = {TOXICOLOGY AND INDUSTRIAL HEALTH},
  year = {2015},
  volume = {31},
  number = {10},
  pages = {911--919},
  issn = {0748-2337},
  doi = {10.1177/0748233713484649},
  url = {https://akademik.atauni.edu.tr/yayinlar/55959-ultrasonic-synthesis-characterization-of-aminoketones-by-bismuthiii-triflate-and}
}