Makale
Tam Makale
Uluslararası
2018
Therapeutic effects of oleuropein on cisplatin-induced pancreas injury in rats
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
Cilt 14 · Sayı 3 · ss. 671–678 · 01.04.2018
Özet
Aims: Cisplatin (CIS) is an influential chemotherapeutic agent in the treatment of several types of malignant solid tumors, but its clinical use is related with ototoxicity. Oleuropein (OLE) is a natural antioxidant and scavenging free radicals. Here, we first explore the efficacy of OLE in pancreas against to the toxicity of CIS and also analyses its mechanism.
Anahtar kelimeler
oxidative stress
melatonin
oxidative DNA damage
ANTIOXIDANT ACTIVITY
GENOTOXICITY
antioxidant
histopathology
OLEUROPEIN
cisplatin
BIOLOGICAL-ACTIVITIES
Pancreas
Olive oil
INDUCED TESTICULAR TOXICITY
PREVENTS
POLYPHENOL
AGENT
Atıf için künye
BAKIR, M., Geyikoğlu, F., Koç, K., & Cerig, S. (2018). Therapeutic effects of oleuropein on cisplatin-induced pancreas injury in rats. JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 14(3), 671–678. https://doi.org/10.4103/jcrt.jcrt_1040_16
BibTeX
@article{bakir2018-55774,
author = {BAKIR, Murat and Geyikoğlu, Fatime and Koç, Kübra and Cerig, Salim},
title = {Therapeutic effects of oleuropein on cisplatin-induced pancreas injury in rats},
journal = {JOURNAL OF CANCER RESEARCH AND THERAPEUTICS},
year = {2018},
volume = {14},
number = {3},
pages = {671--678},
issn = {0973-1482},
doi = {10.4103/jcrt.jcrt_1040_16},
url = {https://akademik.atauni.edu.tr/yayinlar/55774-therapeutic-effects-of-oleuropein-on-cisplatin-induced-pancreas-injury-in-rats}
}