Design and synthesis of novel indoline-(thio)urea hybrids

Lafzi, Ferruh; Kılıç, Haydar; Tanriver, Gamze; Avci, Oykum Naz; Catak, Saron; SARAÇOĞLU, Nurullah

doi:10.1080/00397911.2019.1675706

Makale Tam Makale Uluslararası 2019

Design and synthesis of novel indoline-(thio)urea hybrids

Ferruh Lafzi, Haydar Kılıç, Gamze Tanriver, Oykum Naz Avci, Saron Catak, Nurullah SARAÇOĞLU

SYNTHETIC COMMUNICATIONS Cilt 49 · Sayı 24 · ss. 3510–3527 · 01.12.2019

DOI ile aç

Özet

A series of novel indoline-(thio)urea were designed and prepared using indoline(s) as a new platform and tested as organocatalysts in the Michael and Morita?Baylis?Hillman reactions. Most of the compounds were found to be very active catalysts although they did not promote the enantioselectivity. As agents for the conversion of thiocarbonyl compounds into carbonyl compounds, potentials of PIFA and DDQ were also displayed. Furthermore, DFT calculations rationalized the experimentally observed non-enantioselectivity of the catalysts.

Anahtar kelimeler

amino acids Thiourea urea conjugate addition density functional calculations Morita?Baylis?Hillman organocatalyst ORGANOCATALYSTS

Atıf için künye

Lafzi, F., Kılıç, H., Tanriver, G., Avci, O. N., Catak, S., & SARAÇOĞLU, N. (2019). Design and synthesis of novel indoline-(thio)urea hybrids. SYNTHETIC COMMUNICATIONS, 49(24), 3510–3527. https://doi.org/10.1080/00397911.2019.1675706

BibTeX

@article{lafzi2019-55541,
  author = {Lafzi, Ferruh and Kılıç, Haydar and Tanriver, Gamze and Avci, Oykum Naz and Catak, Saron and SARAÇOĞLU, Nurullah},
  title = {Design and synthesis of novel indoline-(thio)urea hybrids},
  journal = {SYNTHETIC COMMUNICATIONS},
  year = {2019},
  volume = {49},
  number = {24},
  pages = {3510--3527},
  issn = {0039-7911},
  doi = {10.1080/00397911.2019.1675706},
  url = {https://akademik.atauni.edu.tr/yayinlar/55541-design-and-synthesis-of-novel-indoline-thiourea-hybrids}
}