Selectfluor and alcohol-mediated synthesis of bicyclic oxyfluorination compounds by Wagner-Meerwein rearrangement
Özet
Herein, we report the first environmentally friendly systematic fluoroalkoxylation reactions in bicyclic systems. New oxyfluorination products were obtained with excellent yields (up to 98%) via Wagner-Meerwein rearrangement using benzonorbornadiene and the chiral natural compound (+)-camphene as bicyclic alkenes, selectfluor as an electrophilic fluorine source, and water and various alcohols as nucleophile sources. The structure of bicyclic oxy- and alkoxyfluorine compounds was determined by NMR and QTOFMS analyses.
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
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SKA 13: İklim Eylemi
Atıf için künye
Dağalan, Z., Çelikoğlu, M. H., Nişancı, B., Çelik, S., & Koçak, R. (2024). Selectfluor and alcohol-mediated synthesis of bicyclic oxyfluorination compounds by Wagner-Meerwein rearrangement. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 20, 1462–1467. https://doi.org/10.3762/bjoc.20.129
BibTeX
@article{dagalan2024-54213,
author = {Dağalan, Ziya and Çelikoğlu, Muhammed Hanifi and Nişancı, Bilal and Çelik, Saffet and Koçak, Ramazan},
title = {Selectfluor and alcohol-mediated synthesis of bicyclic oxyfluorination compounds by Wagner-Meerwein rearrangement},
journal = {BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY},
year = {2024},
volume = {20},
pages = {1462--1467},
issn = {1860-5397},
doi = {10.3762/bjoc.20.129},
url = {https://akademik.atauni.edu.tr/yayinlar/54213-selectfluor-and-alcohol-mediated-synthesis-of-bicyclic-oxyfluorination-compounds}
}