Heterogeneous Catalytic Reductive Amination of Carbonyl Compounds with Ni-Al Alloy in Water as Solvent and Hydrogen Source
Özet
The heterogeneous catalytic reductive amination of carbon-
yl compounds has been achieved by reactions of ammonium hydroxide
and various amines with ketones and aldehydes. The process is based
on the application of Raney type Ni-Al alloy in an aqueous medium. The
reaction of the carbonyl compounds with the amine provided the cor-
responding Schiff bases that immediately underwent a reduction to
provide primary and secondary amines as products. The controlled re-
action of the Al content of the alloy with the solvent water generates
hydrogen, and the in situ formed Raney Ni
®
serves as a hydrogenation
catalyst. The method is a simple and efficient way of preparing a broad
variety of primary and secondary amines.
Anahtar kelimeler
Atıf için künye
Schäfer, C., Nişancı, B., Bere, M. P., Daştan, A., & Török, B. (2016). Heterogeneous Catalytic Reductive Amination of Carbonyl Compounds with Ni-Al Alloy in Water as Solvent and Hydrogen Source. Synthesis (Germany), 48(18), 3127–3133. https://doi.org/10.1055/s-0035-1561647
BibTeX
@article{schafer2016-54203,
author = {Schäfer, Christian and Nişancı, Bilal and Bere, Matthew P. and Daştan, Arif and Török, Béla},
title = {Heterogeneous Catalytic Reductive Amination of Carbonyl Compounds with Ni-Al Alloy in Water as Solvent and Hydrogen Source},
journal = {Synthesis (Germany)},
year = {2016},
volume = {48},
number = {18},
pages = {3127--3133},
issn = {0039-7881},
doi = {10.1055/s-0035-1561647},
url = {https://akademik.atauni.edu.tr/yayinlar/54203-heterogeneous-catalytic-reductive-amination-of-carbonyl-compounds-with-ni-al}
}