Catalyst/Metal/Solvent-Free Markovnikov Hydrothiolation of Unactivated Alkenes with Dithiocarbamic Acids
Özet
Catalyst-free Markovnikov-selective hydrothiolation of unactivated alkenes still remains a great challenge. Herein, we develop a catalyst/metal/solvent-free methodology for the Markovnikov hydrothiolation of unactivated alkenes with in situ prepared dithiocarbamic acids, providing a wide array of alkyl dithiocarbamates. A variety of terminal, internal, cyclic, and acyclic unactivated alkenes were applied successfully in this protocol. This three-component thiol-ene reaction can be considered as a new family of click reactions.
Atıf için künye
Halimehjani, A. Z., Dağalan, Z., Marjani, Z., Gunduz, F., Daştan, A., & Nişancı, B. (2024). Catalyst/Metal/Solvent-Free Markovnikov Hydrothiolation of Unactivated Alkenes with Dithiocarbamic Acids. JOURNAL OF ORGANIC CHEMISTRY, 89(8), 5353–5362. https://doi.org/10.1021/acs.joc.3c02722
BibTeX
@article{halimehjani2024-54189,
author = {Halimehjani, Azim Ziyaei and Dağalan, Ziya and Marjani, Zahra and Gunduz, Figen and Daştan, Arif and Nişancı, Bilal},
title = {Catalyst/Metal/Solvent-Free Markovnikov Hydrothiolation of Unactivated Alkenes with Dithiocarbamic Acids},
journal = {JOURNAL OF ORGANIC CHEMISTRY},
year = {2024},
volume = {89},
number = {8},
pages = {5353--5362},
issn = {0022-3263},
doi = {10.1021/acs.joc.3c02722},
url = {https://akademik.atauni.edu.tr/yayinlar/54189-catalystmetalsolvent-free-markovnikov-hydrothiolation-of-unactivated-alkenes}
}