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Makale Tam Makale Uluslararası 2014

One-Pot Synthesis of Mannich Bases Under Solvent-Free Conditions

ONUR DEMİRKOL, DİLEK AKBAŞLAR, Sultan Giray, Barış Anıl

SYNTHETIC COMMUNICATIONS Cilt 44 · Sayı 9 · ss. 1279–1285 · 03.05.2014
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Özet

A mild and practically convenient one-pot procedure for the Mannich reaction via condensation of amines, aldehydes and malonates, beta-ketoesters, or beta-dicarbonyl compounds has been carried out without using any organic solvent, metallic catalyst, or Lewis acids or bases at room temperature. The present protocol offers several advantages, such as goods yields, simple procedure with easy workup, and the absence of any volatile, hazardous organic solvents and metallic catalyst.

Anahtar kelimeler

SYSTEM ACID DERIVATIVES Mannich bases KETONES One-pot synthesis Imines stereoselective synthesis 3-COMPONENT SYNTHESIS SOLVENT-FREE SYNTHESIS Aldehydes beta-dicarbonyl compounds Multicomponent reaction AMINO CARBONYL-COMPOUNDS HIGHLY EFFICIENT CATALYST

Atıf için künye

DEMİRKOL, O., AKBAŞLAR, D., Giray, S., & Anıl, B. (2014). One-Pot Synthesis of Mannich Bases Under Solvent-Free Conditions. SYNTHETIC COMMUNICATIONS, 44(9), 1279–1285. https://doi.org/10.1080/00397911.2013.853191

BibTeX 
@article{demirkol2014-341178,
  author = {DEMİRKOL, ONUR and AKBAŞLAR, DİLEK and Giray, Sultan and Anıl, Barış},
  title = {One-Pot Synthesis of Mannich Bases Under Solvent-Free Conditions},
  journal = {SYNTHETIC COMMUNICATIONS},
  year = {2014},
  volume = {44},
  number = {9},
  pages = {1279--1285},
  issn = {0039-7911},
  doi = {10.1080/00397911.2013.853191},
  url = {https://akademik.atauni.edu.tr/yayinlar/341178-one-pot-synthesis-of-mannich-bases-under-solvent-free-conditions}
}