Synthesis and chemistry of unusual bicyclic endoperoxides containing the pyridazine ring
Özet
Inverse-Diels-Alder reaction of dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate with unsaturated bicyclic endoperoxides gave the bicyclic endoperoxides containing the pyridazine ring. The NEt3 and CoTPP (TPP = tetraphenylporphyrin) catalyzed reaction of endoperoxide 8 resulted in the formation of hydroxy ketone 11 and cis-diol 9. Cleavage of the peroxide linkage in 8 with thiourea provided cis-diol 9. Oxidation of hydroxy ketone 11 and cis-diol 9 led to the phthalazine-5,8-dione 10. Furthermore, the various transformations of the other endoperoxides 19, 20, 22, 23, and 30 resulted in the formation of pyridazine derivatives.
Atıf için künye
Özer, G., Saracoglu, N., & BALCI, M. (2003). Synthesis and chemistry of unusual bicyclic endoperoxides containing the pyridazine ring. JOURNAL OF ORGANIC CHEMISTRY, 68(18), 7009–7015. https://doi.org/10.1021/jo0345300
BibTeX
@article{ozer2003-334678,
author = {Özer, Galip and Saracoglu, Nurullah and BALCI, METİN},
title = {Synthesis and chemistry of unusual bicyclic endoperoxides containing the pyridazine ring},
journal = {JOURNAL OF ORGANIC CHEMISTRY},
year = {2003},
volume = {68},
number = {18},
pages = {7009--7015},
issn = {0022-3263},
doi = {10.1021/jo0345300},
url = {https://akademik.atauni.edu.tr/yayinlar/334678-synthesis-and-chemistry-of-unusual-bicyclic-endoperoxides-containing-the}
}