Journal of the Hellenic Veterinary Medical Society

Propolis is a product with many benefits, honey bees produce propolis by mixing the resin substances they collect from the bark, leaves, and plant secretions of trees with honey, wax, pollen, and their salivary enzymes. They use this product for several purposes including protecting bee larvae, honey stores, and honeycombs from in-fections, repairing damaged areas, covering holes and cracks in the hive. It was also used in folk medicine with its antimicrobial and healing effects since ancient times. Beside these properties, with the advancements in science, vari-ous other properties of propolis like immunomodulatory, anti-inflammatory, antitumor, antioxidant, anticarcinogenic, antiprotozoal, antiviral,antiulcer, local anesthetic, cytotoxic, and many more were also discovered.After growing of the concerns about residue problems in food, arbitrary usage of antibiotics in animal farming was restricted or banned by many countries.This led to an increase in the demand for organic products in the public and drove scientists to search for new natural alternative feed additives that can show similar effects with antibiotics in order to prevent economic losses caused by the restriction. The aim of this study was to discuss the effects of propolis in ruminants as a feed ad-ditive and its usability as a natural alternative to antibiotics by analyzing studies on the field.