EFFECTS OF ELF5 AND FGF21 GENE POLYMORPHISMS ON SOME PERFORMANCE TRAITS IN BROWN SWISS CATTLE

In this study we aimed to determined molecular marker polymorphism in the ELF5 (E74-Like Factorr 5)

and FGF21 (Fibroblast Growth Factor 21) which effected the performance traits of cattle. We are used as

material the Brown Swiss breed DNA samples. PCR analysis were made for the three different genes and

then DNA samples sequence analysis were applied to some of the samples in each different gene region and

were defined its polymorphic regions. In the result of DNA sequence analysis for ELF5 and FGF21 gene

regions: for the 2. intron of ELF5 gene;, g.65825359 C/T and g.65825499 G/A transistions, for the 5. exon

region of ELF5 gene; G.65825909 T/C, g.65826062 G/A, g.65826123 A/C, g.65826134 C/T; and g.

65826138 T/C polymorphic region, for the 1. exon region of the FGF21 gene; G.55834828 C/G

polymorphic region, for the 3. exon region of FGF21 gene; g.55836088 G/T and g.55836007 C/A

polymorphic regions were defined. There was non-significant as statistically the relationship between the

polymorphic regions determined for the ELF5 and FGF21 gene and lactation milk yields, 305-days milk

yields, daily milk yields, lactation times, peak milk yields, peak day yields and average peak milk yields of

Brown Swiss breed (P>0.05). However, it is suggested to investigate the marker ability of polymorphic

regions determined for future studies in the animal breeding

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