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Makale Tam Makale Uluslararası 2020

Comparative Analysis of Far East Sikhotinsky Rhododendron (Rh. sichotense) and East Siberian Rhododendron (Rh. adamsii) Using Supercritical CO2-Extraction and HPLC-ESI-MS/MS Spectrometry

Mayya Razgonova, Alexander Zakharenko, Sezai Ercişli, Vasily Grudev, Kirill Golokhvast

MOLECULES Cilt 25 · Sayı 17 · 01.09.2020
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Özet

Rhododendron sichotensePojark. andRhododendron adamsiiRheder have been actively used in ethnomedicine in Mongolia, China and Buryatia (Russia) for centuries, as an antioxidant, immunomodulating, anti-inflammatory, vitality-restoring agent. These plants contain various phenolic compounds and fatty acids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO2) extraction has been shown to be the method of choice for the recovery of these naturally occurring compounds. Operative parameters and working conditions have been optimized by experimenting with different pressures (300-400 bar), temperatures (50-60 degrees C) and CO(2)flow rates (50 mL/min) with 1% ethanol as co-solvent. The extraction time varied from 60 to 70 min. A HPLC-UV-VIS-ESI-MS/MS technique was applied to detect target analytes. A total of 48 different biologically active components have been identified in theRh. adamsiiSC-CO(2)extracts. A total of 31 different biologically active components have been identified in theRh. sichotenseSC-CO(2)extracts.

Anahtar kelimeler

EXTRACTION MS leaves L. phenolic compounds Flavonoids ESSENTIAL OIL CHROMATOGRAPHY SUPERCRITICAL-FLUID EXTRACTION ACIDS HPLC-MS Rhododendron sichotense Rhododendron adamsii LEDUM-PALUSTRE ERICACEAE

Atıf için künye

Razgonova, M., Zakharenko, A., Ercişli, S., Grudev, V., & Golokhvast, K. (2020). Comparative Analysis of Far East Sikhotinsky Rhododendron (Rh. sichotense) and East Siberian Rhododendron (Rh. adamsii) Using Supercritical CO2-Extraction and HPLC-ESI-MS/MS Spectrometry. MOLECULES, 25(17). https://doi.org/10.3390/molecules25173774

BibTeX 
@article{razgonova2020-264775,
  author = {Razgonova, Mayya and Zakharenko, Alexander and Ercişli, Sezai and Grudev, Vasily and Golokhvast, Kirill},
  title = {Comparative Analysis of Far East Sikhotinsky Rhododendron (Rh. sichotense) and East Siberian Rhododendron (Rh. adamsii) Using Supercritical CO2-Extraction and HPLC-ESI-MS/MS Spectrometry},
  journal = {MOLECULES},
  year = {2020},
  volume = {25},
  number = {17},
  issn = {1420-3049},
  doi = {10.3390/molecules25173774},
  url = {https://akademik.atauni.edu.tr/yayinlar/264775-comparative-analysis-of-far-east-sikhotinsky-rhododendron-rh-sichotense-and-east}
}