Synergistic effects of high-fat diets on obesity

Obesity is a worldwide severe problem caused by abnormal fat accumulation. It is responsible for several health effects such as energy imbalance between calories consumed and calories expended, gallbladder disease, coronary heart disease, type 2 diabetes, hypertension, osteoarthritis, and high blood cholesterol. In this book chapter, we are focusing on the synergistic effect of the high-fed diet on obesity. High fed diet is the major diet that comprises saturated and unsaturated fats. The synergistic effect of high-fed diet observed on body composition, weight gain, adipose tissue, the role of hormones viz., ghrelin, leptin, and insulin, sleep regulation, beta-cell failure, and aging effect on beta-cell.