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Morin attenuates acrylamide-induced testicular toxicity in rats by regulating the NF-kappa B, Bax/Bcl-2 and PI3K/Akt/mTOR signaling pathways

Sefa Küçükler, Cuneyt Caglayan, Ekrem Darendelioğlu, Fatih Mehmet Kandemir

Life sciences Cilt 261 · 01.11.2020
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Özet

Aim: Acrylamide (AC) is a carcinogenic substance which is formed during the heating of starchy foods at high temperatures and constitutes an important risk for human health. Therefore, reducing the detrimental effects of AC has become an important research topic. This study was performed to evaluate the protective effect of morin against the testicular toxicity induced by AC in male rats.

Anahtar kelimeler

oxidative stress PROLIFERATION INFLAMMATION CELLS apoptosis Autophagy EXTRACT INDUCED NEUROTOXICITY INDUCED OXIDATIVE STRESS Testicular toxicity TRANSCRIPTION Acrylamide PROSTATE Morin

Sürdürülebilir Kalkınma Amaçları

  • SKA 3: Sağlıklı Bireyler

Atıf için künye

Küçükler, S., Caglayan, C., Darendelioğlu, E., & Kandemir, F. M. (2020). Morin attenuates acrylamide-induced testicular toxicity in rats by regulating the NF-kappa B, Bax/Bcl-2 and PI3K/Akt/mTOR signaling pathways. Life sciences, 261. https://doi.org/10.1016/j.lfs.2020.118301

BibTeX
@article{kucukler2020-260901,
  author = {Küçükler, Sefa and Caglayan, Cuneyt and Darendelioğlu, Ekrem and Kandemir, Fatih Mehmet},
  title = {Morin attenuates acrylamide-induced testicular toxicity in rats by regulating the NF-kappa B, Bax/Bcl-2 and PI3K/Akt/mTOR signaling pathways},
  journal = {Life sciences},
  year = {2020},
  volume = {261},
  issn = {0024-3205},
  doi = {10.1016/j.lfs.2020.118301},
  url = {https://akademik.atauni.edu.tr/yayinlar/260901-morin-attenuates-acrylamide-induced-testicular-toxicity-in-rats-by-regulating}
}