Makale
Tam Makale
Uluslararası
2019
Rutin ameliorates mercuric chloride-induced hepatotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
Cilt 56 · ss. 60–68 · 01.12.2019
Özet
Objective: Mercury is a global environmental pollutant and is responsible for several organ pathophysiology including oxidative stress-induced liver disorders. Therefore, the present study was conducted to evaluate the potential ameliorative effects of rutin on mercury chloride (HgCl2)-induced hepatotoxicity in adult male rats.
Anahtar kelimeler
INFLAMMATION
Activation
ANTIOXIDANT ACTIVITY
toxicity
apoptosis
EXPOSURE
liver
Luteolin
CYCLOOXYGENASE-2
hepatotoxicity
rutin
EGFR
SODIUM SELENITE
Mercuric chloride
SIGNALING PATHWAY
Epidermal growth factor receptor
Atıf için künye
Yıldırım, S., Kandemir, F. M., Darendelioglu, E., Yıldırım, S., Küçükler, S., & Dörtbudak, M. B. (2019). Rutin ameliorates mercuric chloride-induced hepatotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, 56, 60–68. https://doi.org/10.1016/j.jtemb.2019.07.011
BibTeX
@article{yildirim2019-259262,
author = {Yıldırım, Serkan and Kandemir, Fatih Mehmet and Darendelioglu, Ekrem and Yıldırım, Serkan and Küçükler, Sefa and Dörtbudak, Muhammet Bahaeddin},
title = {Rutin ameliorates mercuric chloride-induced hepatotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis},
journal = {JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY},
year = {2019},
volume = {56},
pages = {60--68},
issn = {0946-672X},
doi = {10.1016/j.jtemb.2019.07.011},
url = {https://akademik.atauni.edu.tr/yayinlar/259262-rutin-ameliorates-mercuric-chloride-induced-hepatotoxicity-in-rats-via}
}