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Makale Tam Makale Uluslararası 2019

Rutin protects mercuric chloride‐induced nephrotoxicity via targeting of aquaporin 1 level, oxidative stress, apoptosis and inflammation in rats

Serkan Yıldırım, Fatih Mehmet Kandemir, Serkan Yıldırım, Sefa Küçükler, Gizem Eser

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY Cilt 54 · ss. 69–78 · 01.07.2019
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Özet

Objective: Mercury is a dangerous industrial and environmental pollutant which induces severe damage in diverse organs in animal and humans. The aim of this study was to investigate the protective effect of rutin (50 and 100 mg/kg body weight) against mercuric chloride (HgCl2) (1.23 mg/kg b.w.) toxicity in rats.

Anahtar kelimeler

oxidative stress EXPRESSION DAMAGE INFLAMMATION Activation ANTIOXIDANT ACTIVITY toxicity apoptosis EXTRACT NF-KAPPA-B nephrotoxicity rutin SODIUM SELENITE Zingerone Mercuric chloride DIETARY LUTEOLIN

Atıf için künye

Yıldırım, S., Kandemir, F. M., Yıldırım, S., Küçükler, S., & Eser, G. (2019). Rutin protects mercuric chloride‐induced nephrotoxicity via targeting of aquaporin 1 level, oxidative stress, apoptosis and inflammation in rats. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, 54, 69–78. https://doi.org/10.1016/j.jtemb.2019.04.007

BibTeX
@article{yildirim2019-259198,
  author = {Yıldırım, Serkan and Kandemir, Fatih Mehmet and Yıldırım, Serkan and Küçükler, Sefa and Eser, Gizem},
  title = {Rutin protects mercuric chloride‐induced nephrotoxicity via targeting of aquaporin 1 level, oxidative stress, apoptosis and inflammation in rats},
  journal = {JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY},
  year = {2019},
  volume = {54},
  pages = {69--78},
  issn = {0946-672X},
  doi = {10.1016/j.jtemb.2019.04.007},
  url = {https://akademik.atauni.edu.tr/yayinlar/259198-rutin-protects-mercuric-chlorideinduced-nephrotoxicity-via-targeting-of}
}