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Makale Derleme Uluslararası 2024

Clinical practice guidelines for the diagnosis and treatment of scabies

SONER UZUN, MURAT DURDU, Aslan Yurekli, MEHMET KAMİL MÜLAYİM, MELİH AKYOL, SEVTAP VELİPAŞAOĞLU, MEHMET HARMAN, Aysegul Taylan-Ozkan, EKİN BOZKURT ŞAVK, DEVRİM DEMİR DORA, LEVENT DÖNMEZ, Umut Gazi, Habibullah Aktas, AYSUN ŞİKAR AKTÜRK, Guelay Demir, Fatih Goktay, Mehmet Salih Gürel, Nese G. Gurok, Ayse S. Karadag, oezlem S. Kucuk, Cagri Turan, Muege G. Ozden, Zeynep Karaca Ural, ORÇUN ZORBOZAN, Kosta Y. Mumcuoglu

INTERNATIONAL JOURNAL OF DERMATOLOGY Cilt 63 · Sayı 12 · ss. 1642–1656 · 01.12.2024
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Özet

Scabies, caused by the Sarcoptes scabiei var hominis mite burrowing into the skin, is a highly contagious disease characterized by intense nocturnal itching. Its global impact is considerable, affecting more than 200 million individuals annually and posing significant challenges to healthcare systems worldwide. Transmission occurs primarily through direct skin-to-skin contact, contributing to its widespread prevalence and emergence as a substantial public health concern affecting large populations. This review presents consensus-based clinical practice guidelines for diagnosing and managing scabies, developed through the fuzzy Delphi method by dermatology, parasitology, pediatrics, pharmacology, and public health experts. The presence of burrows containing adult female mites, their eggs, and excreta is the diagnostic hallmark of scabies. Definitive diagnosis typically involves direct microscopic examination of skin scrapings obtained from these burrows, although dermoscopy has become a diagnostic tool in clinical practice. Treatment modalities encompass topical agents, such as permethrin, balsam of Peru, precipitated sulfur, and benzyl benzoate. In cases where topical therapy proves inadequate or in instances of crusted scabies, oral ivermectin is recommended as a systemic treatment option. This comprehensive approach addresses the diagnostic and therapeutic challenges associated with scabies, optimizing patient care, and management outcomes.

Anahtar kelimeler

treatment PREVENTION elimination Scabies diagnostics infestations neglected tropical diseases

Atıf için künye

UZUN, S., DURDU, M., Yurekli, A., MÜLAYİM, M. K., AKYOL, M., VELİPAŞAOĞLU, S., HARMAN, M., Taylan-Ozkan, A., BOZKURT ŞAVK, E., DEMİR DORA, D., DÖNMEZ, L., Gazi, U., Aktas, H., ŞİKAR AKTÜRK, A., Demir, G., Goktay, F., Gürel, M. S., Gurok, N. G., Karadag, A. S., … Mumcuoglu, K. Y. (2024). Clinical practice guidelines for the diagnosis and treatment of scabies. INTERNATIONAL JOURNAL OF DERMATOLOGY, 63(12), 1642–1656. https://doi.org/10.1111/ijd.17327

BibTeX
@article{uzun2024-246253,
  author = {UZUN, SONER and DURDU, MURAT and Yurekli, Aslan and MÜLAYİM, MEHMET KAMİL and AKYOL, MELİH and VELİPAŞAOĞLU, SEVTAP and HARMAN, MEHMET and Taylan-Ozkan, Aysegul and BOZKURT ŞAVK, EKİN and DEMİR DORA, DEVRİM and DÖNMEZ, LEVENT and Gazi, Umut and Aktas, Habibullah and ŞİKAR AKTÜRK, AYSUN and Demir, Guelay and Goktay, Fatih and Gürel, Mehmet Salih and Gurok, Nese G. and Karadag, Ayse S. and Kucuk, oezlem S. and Turan, Cagri and Ozden, Muege G. and Karaca Ural, Zeynep and ZORBOZAN, ORÇUN and Mumcuoglu, Kosta Y.},
  title = {Clinical practice guidelines for the diagnosis and treatment of scabies},
  journal = {INTERNATIONAL JOURNAL OF DERMATOLOGY},
  year = {2024},
  volume = {63},
  number = {12},
  pages = {1642--1656},
  issn = {0011-9059},
  doi = {10.1111/ijd.17327},
  url = {https://akademik.atauni.edu.tr/yayinlar/246253-clinical-practice-guidelines-for-the-diagnosis-and-treatment-of-scabies}
}