Makale
Tam Makale
Uluslararası
2019
THE IN VITRO CYTOTOXICITY, GENOTOXICITY AND OXIDATIVE DAMAGE POTENTIAL OF THE ORAL DIPEPTIDYL PEPTIDASE-4 INHIBITOR, LINAGLIPTIN, ON CULTURED HUMAN MONONUCLEAR BLOOD CELLS
ACTA ENDOCRINOLOGICA-BUCHAREST
Cilt 15 · Sayı 1 · ss. 9–15 · 01.01.2019
Özet
Background. Linagliptin (LNG) is a selective dipeptidyl peptidase-4 (DPP-4) inhibitor that ameliorates blood glucose control of patients with type 2 diabetes, without developing hypoglycemic risk and weight gain with a good clinical and biological tolerance profile. To the best of our knowledge, its cytotoxic, genotoxic and oxidative effects have never been studied on any cell line.
Anahtar kelimeler
stress
oxidative stress
TYPE-2
MANAGEMENT
EFFICACY
THERAPY
SAFETY
GENOTOXICITY
cytotoxicity
TOLERABILITY
Sitagliptin
GLYCEMIC CONTROL
DPP-4 inhibitor
linagliptin
DPP-4 INHIBITORS
Sürdürülebilir Kalkınma Amaçları
-
SKA 3: Sağlıklı Bireyler
Atıf için künye
Cadirci, K., Türkez, H., & Ozdemir, O. (2019). THE IN VITRO CYTOTOXICITY, GENOTOXICITY AND OXIDATIVE DAMAGE POTENTIAL OF THE ORAL DIPEPTIDYL PEPTIDASE-4 INHIBITOR, LINAGLIPTIN, ON CULTURED HUMAN MONONUCLEAR BLOOD CELLS. ACTA ENDOCRINOLOGICA-BUCHAREST, 15(1), 9–15. https://doi.org/10.4183/aeb.2019.9
BibTeX
@article{cadirci2019-244962,
author = {Cadirci, K. and Türkez, Hasan and Ozdemir, O.},
title = {THE IN VITRO CYTOTOXICITY, GENOTOXICITY AND OXIDATIVE DAMAGE POTENTIAL OF THE ORAL DIPEPTIDYL PEPTIDASE-4 INHIBITOR, LINAGLIPTIN, ON CULTURED HUMAN MONONUCLEAR BLOOD CELLS},
journal = {ACTA ENDOCRINOLOGICA-BUCHAREST},
year = {2019},
volume = {15},
number = {1},
pages = {9--15},
issn = {1841-0987},
doi = {10.4183/aeb.2019.9},
url = {https://akademik.atauni.edu.tr/yayinlar/244962-the-in-vitro-cytotoxicity-genotoxicity-and-oxidative-damage-potential-of-the}
}