Current Status of COVID-19 Therapies and Drug Repositioning Applications
Özet
The rapid and global spread of a new human coronavirus (SARS-CoV-2) has produced an immediate urgency to discover promising targets for the treatment of COVID-19. Drug repositioning is an attractive approach that can facilitate the drug discovery process by repurposing existing pharmaceuticals to treat illnesses other than their primary indications. Here, we review current information concerning the global health issue of COVID-19 including promising approved drugs and ongoing clinical trials for prospective treatment options. In addition, we describe computational approaches to be used in drug repurposing and highlight examples of in silico studies of drug development efforts against SARS-CoV-2.
Sürdürülebilir Kalkınma Amaçları
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SKA 3: Sağlıklı Bireyler
Atıf için künye
Altay, O., Mohammadi, E., Lam, S., Türkez, H., Boren, J., Nielsen, J., Uhlen, M., & Mardinoglu, A. (2020). Current Status of COVID-19 Therapies and Drug Repositioning Applications. ISCIENCE, 23(7). https://doi.org/10.1016/j.isci.2020.101303
BibTeX
@article{altay2020-244941,
author = {Altay, Ozlem and Mohammadi, Elyas and Lam, Simon and Türkez, Hasan and Boren, Jan and Nielsen, Jens and Uhlen, Mathias and Mardinoglu, Adil},
title = {Current Status of COVID-19 Therapies and Drug Repositioning Applications},
journal = {ISCIENCE},
year = {2020},
volume = {23},
number = {7},
issn = {2589-0042},
doi = {10.1016/j.isci.2020.101303},
url = {https://akademik.atauni.edu.tr/yayinlar/244941-current-status-of-covid-19-therapies-and-drug-repositioning-applications}
}