Makale
Tam Makale
Uluslararası
2020
Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation
European journal of medicinal chemistry
Cilt 186 · 15.01.2020
Özet
To date, drugs that hit a single target are inadequate for the treatment of neurodegenerative diseases, such as Alzheimer's or Parkinson's diseases. The development of multitarget ligands, able to interact with the different pathways involved in the progession of these disorders, represents a great challenge for medicinal chemists.
Anahtar kelimeler
DESIGN
ACID
INHIBITORS
Alzheimer's disease
DERIVATIVES
POLYPHENOLS
DISCOVERY
BETA
HYBRID
POLYPHENOL
Lipoic acid
ESTER
Atıf için künye
Pagoni, A., Marinelli, L., Di Stefano, A., Ciulla, M., Türkez, H., Mardinoglu, A., Vassiliou, S., & Cacciatore, I. (2020). Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation. European journal of medicinal chemistry, 186. https://doi.org/10.1016/j.ejmech.2019.111880
BibTeX
@article{pagoni2020-244889,
author = {Pagoni, Aikaterini and Marinelli, Lisa and Di Stefano, Antonio and Ciulla, Michele and Türkez, Hasan and Mardinoglu, Adil and Vassiliou, Stamatia and Cacciatore, Ivana},
title = {Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation},
journal = {European journal of medicinal chemistry},
year = {2020},
volume = {186},
issn = {0223-5234},
doi = {10.1016/j.ejmech.2019.111880},
url = {https://akademik.atauni.edu.tr/yayinlar/244889-novel-anti-alzheimer-phenol-lipoyl-hybrids-synthesis-physico-chemical}
}