In vitro assessment of genotoxic and oxidative effects of zinc borate
Özet
Zinc borate is used as flame retardant for plastics and cellulose fibers, paper, rubber, and textiles. Despite its wide industrial use, there is limited information concerning its toxicity. The aim of the present study was to investigate the concentration dependence (0-280mg L-1) of its genotoxic activity on cultured human lymphocytes by using sister chromatid exchange and chromosomal aberration assays. Total antioxidant capacity and the extent of oxidative stress were also determined. Zinc borate was found to be non-genotoxic at all tested concentrations. It exhibited antioxidant activity at concentrations lower than 40mg L-1, and total oxidative stress levels were not changed at any applied concentration of zinc borate.
Anahtar kelimeler
Atıf için künye
ÇELİKEZEN, F. Ç., TÜRKEZ, H., & Türkez, H. (2014). In vitro assessment of genotoxic and oxidative effects of zinc borate. Toxicological and Environmental Chemistry, 96(5), 777–782. https://doi.org/10.1080/02772248.2014.983510
BibTeX
@article{celikezen2014-244884,
author = {ÇELİKEZEN, FATİH ÇAĞLAR and TÜRKEZ, HASAN and Türkez, Hasan},
title = {In vitro assessment of genotoxic and oxidative effects of zinc borate},
journal = {Toxicological and Environmental Chemistry},
year = {2014},
volume = {96},
number = {5},
pages = {777--782},
issn = {0277-2248},
doi = {10.1080/02772248.2014.983510},
url = {https://akademik.atauni.edu.tr/yayinlar/244884-in-vitro-assessment-of-genotoxic-and-oxidative-effects-of-zinc-borate}
}