Makale
Tam Makale
Uluslararası
2015
The lung endothelin system: a potent therapeutic target with bosentan for the amelioration of lung alterations in a rat model of diabetes mellitus
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
Cilt 38 · Sayı 9 · ss. 987–998 · 01.09.2015
Özet
Purpose The aim of this study is to show the effect of a new mechanism on endothelin (ET) receptors in the physiopathology of diabetes-related pulmonary injury. We tested the hypothesis that dual ET-1 receptor antagonism via bosentan can reverse diabetes-induced lung injury.
Anahtar kelimeler
TISSUE
DYSFUNCTION
oxidative stress
NITRIC-OXIDE
Diabetes
EXPRESSION
COMPLICATIONS
DOUBLE-BLIND
polymicrobial sepsis
Lung injury
BOSENTAN
ENDOTHELIN SYSTEM
RECEPTOR ANTAGONIST BOSENTAN
ETA-RECEPTOR
Sürdürülebilir Kalkınma Amaçları
-
SKA 3: Sağlıklı Bireyler
Atıf için künye
CAYIR, A., Uğan, R. A., Albayrak, A., KÖSE, D., Akpınar, E., Çayır, Y., Atmaca, H. T., Bayraktutan, Z., & KARA, M. (2015). The lung endothelin system: a potent therapeutic target with bosentan for the amelioration of lung alterations in a rat model of diabetes mellitus. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 38(9), 987–998. https://doi.org/10.1007/s40618-015-0282-y
BibTeX
@article{cayir2015-24463,
author = {CAYIR, A. and Uğan, Rüstem Anıl and Albayrak, Abdulmecit and KÖSE, Duygu and Akpınar, Erol and Çayır, Yasemin and Atmaca, H. T. and Bayraktutan, Zafer and KARA, Murat},
title = {The lung endothelin system: a potent therapeutic target with bosentan for the amelioration of lung alterations in a rat model of diabetes mellitus},
journal = {JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION},
year = {2015},
volume = {38},
number = {9},
pages = {987--998},
issn = {0391-4097},
doi = {10.1007/s40618-015-0282-y},
url = {https://akademik.atauni.edu.tr/yayinlar/24463-the-lung-endothelin-system-a-potent-therapeutic-target-with-bosentan-for-the}
}