Possible contribution of the neprilysin/ACE pathway to sepsis in mice

Uğan, Rüstem Anıl; Un, Harun; Gürbüz, Muhammet Ali; Kaya, Gokce; Kahramanlar, Aysenur; Aksakalli-Magden, Zeynep Berna; Halıcı, Zekai; Çadırcı, Elif

doi:10.1016/j.lfs.2020.118177

Makale Tam Makale Uluslararası 2020

Possible contribution of the neprilysin/ACE pathway to sepsis in mice

Rüstem Anıl Uğan, Harun Un, Muhammet Ali Gürbüz, Gokce Kaya, Aysenur Kahramanlar, Zeynep Berna Aksakalli-Magden, Zekai Halıcı, Elif Çadırcı

Life sciences Cilt 258 · 01.10.2020

DOI ile aç

Özet

Aim: Omapatrilat is an antagonist of angiotensin-converting (ACE) and neprilysin-neuropeptidase (NEP) enzymes. The aim of our study is to show that omapatrilat may have beneficial effects as a treatment for polymicrobial sepsis.

Anahtar kelimeler

cytokines mice SEPSIS PERMEABILITY Rat model INFARCTION angiotensin converting enzyme neprilysin omapatrilat ATRIAL-NATRIURETIC-PEPTIDE ACE ACUTE LUNG INJURY VASOPEPTIDASE INHIBITOR OMAPATRILAT ACUTE RESPIRATORY-DISTRESS CANDESARTAN

Sürdürülebilir Kalkınma Amaçları

SKA 3: Sağlıklı Bireyler

Atıf için künye

Uğan, R. A., Un, H., Gürbüz, M. A., Kaya, G., Kahramanlar, A., Aksakalli-Magden, Z. B., Halıcı, Z., & Çadırcı, E. (2020). Possible contribution of the neprilysin/ACE pathway to sepsis in mice. Life sciences, 258. https://doi.org/10.1016/j.lfs.2020.118177

BibTeX

@article{ugan2020-24461,
  author = {Uğan, Rüstem Anıl and Un, Harun and Gürbüz, Muhammet Ali and Kaya, Gokce and Kahramanlar, Aysenur and Aksakalli-Magden, Zeynep Berna and Halıcı, Zekai and Çadırcı, Elif},
  title = {Possible contribution of the neprilysin/ACE pathway to sepsis in mice},
  journal = {Life sciences},
  year = {2020},
  volume = {258},
  issn = {0024-3205},
  doi = {10.1016/j.lfs.2020.118177},
  url = {https://akademik.atauni.edu.tr/yayinlar/24461-possible-contribution-of-the-neprilysinace-pathway-to-sepsis-in-mice}
}