Evaluation of serum salusin-α and β levels in patients with obstructive sleep apnea.

Aim: Salusin-α and salusin-β peptides are crucial in the development of cardiovascular diseaseslike coronary artery disease (CAD). This study compared serum levels of these peptides in patientswith obstructive sleep apnea (OSA), those with both OSA and CAD. Materials & methods: Patientswithout OSA were included in Group 1, those with OSA alone comprised Group 2, and those withOSA and CAD were in Group 3. Results: Salusin-α level was significantly higher in controls than inGroups 2 and 3, while salusin-β levels were significantly higher in Groups 2 and 3 compared with thecontrol group. Conclusion: Salusin-α and -β levels may be parameters that can guide the diagnosisof OSA in patients with a consistent clinical history.